iGMDRD44
| Standard Name | CHEMBL | Pubchem CID | KEGG Drug ID | DRUGBANK ID | Drug Status | Drug targets (TTD) | Drug Type |
|---|---|---|---|---|---|---|---|
| Temozolomide | CHEMBL810 | 5394 | D06067 | DB00853 | Alone | DAP000987 | Small Molecule |
Drug Class:
Alkylating AgentsAlkylating DrugAntineoplastic AgentsAntineoplastic Agents, AlkylatingAntineoplastic and Immunomodulating AgentsAzolesCytochrome P-450 Enzyme InducersHeterocyclic CompoundsHeterocyclic Compounds, 1-RingImidazolesImmunosuppressive AgentsMyelosuppressive AgentsNoxaeToxic ActionsTriazenesDrug Targets:
DNA akylating agentDrug Pathways:
DNA replicationDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 390502 | SERPINA2 | 2 |
| 55252 | ASXL2 | 1 |
| 472 | ATM | 4 |
| 5834 | PYGB | 1 |
| 7157 | TP53 | 1 |
| 4086 | SMAD1 | 1 |
| 546 | ATRX | 1 |
| 3417 | IDH1 | 1 |
| 54894 | RNF43 | 1 |
| 1956 | EGFR | 1 |
| 4609 | MYC | 3 |
| 673 | BRAF | 1 |
| 5781 | PTPN11 | 1 |
| 171023 | ASXL1 | 1 |
| 4255 | MGMT | 3 |
| 4893 | NRAS | 3 |
Gene in drug-gene network: Network Plot
Models in Temozolomide
CLASSFICATION
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