TRPM8


Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in TRPM8


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Term Type
Evidence Type
GO Term ID
GO Des.
MF TAS GO:0005262 calcium channel activity
MF IPI GO:0005515 protein binding
MF IEA GO:0042803 protein homodimerization activity
BP IEA GO:0006874 cellular calcium ion homeostasis
BP IEA GO:0009409 response to cold
BP IEA GO:0016048 detection of temperature stimulus
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Gene expression in normal tissue: TRPM8

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined30Apoptosis regulation3Biosynthesis of secondary metabolites2Proteasome1Protein stability and degradation1Purine metabolism1DNA replication1Stilbenoid, diarylheptanoid and gingerol biosynthesis1Metabolism1Ferroptosis1

Pathways in TRPM8


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Database
Pathway ID
Pathway Des.
kegg hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human)
reactome R-HSA-2672351 Stimuli-sensing channels
reactome R-HSA-3295583 TRP channels
reactome R-HSA-382551 Transport of small molecules
reactome R-HSA-983712 Ion channel transport
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD434 BMS-536924 4
iGMDRD705 Nakiterpiosin 3
iGMDRD6 AM-580 2
iGMDRD105 Triptolide 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TRPM8

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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