MAP4K1

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namemitogen-activated protein kinase kinase kinase kinase 1
OMIM IDMIM:601983
Ensembl IDEnsembl:ENSG00000104814
HGNC IDHGNC:HGNC:6863
PHARMGKB IDPA30609
Map Location19q13.2

GO terms in MAP4K1


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0000165 MAPK cascade
BP IC GO:0000185 activation of MAPKKK activity
BP IDA GO:0006468 protein phosphorylation
BP IDA GO:0007257 activation of JUN kinase activity
BP IBA GO:0007346 regulation of mitotic cell cycle
BP IMP GO:0008283 cell proliferation
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Gene expression in normal tissue: MAP4K1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined18ERK MAPK signaling2Chromatin histone acetylation2Other, kinases1Apoptosis regulation1

Pathways in MAP4K1


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Database
Pathway ID
Pathway Des.
biocarta mapkpathway mapkinase signaling pathway
pid bcr_5pathway BCR signaling pathway
pid kitpathway Signaling events mediated by Stem cell factor receptor (c-Kit)
pid tcr_pathway TCR signaling in naïve CD4+ T cells
pid tcrjnkpathway JNK signaling in the CD4+ TCR pathway
kegg hsa04010 MAPK signaling pathway - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD782 DC-45-A2 3
iGMDRD289 Parthenolide 6
iGMDRD267 Oligomycin A 3
iGMDRD251 ML162 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MAP4K1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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