SRPK2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| SRSF protein kinase 2 | MIM:602980 | Ensembl:ENSG00000135250 | HGNC:HGNC:11306 | PA36130 | 7q22.3 |
GO terms in SRPK2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005730 | nucleolus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005829 | cytosol |
| BP | IBA | GO:0000245 | spliceosomal complex assembly |
| BP | IDA | GO:0000245 | spliceosomal complex assembly |
| BP | ISS | GO:0001525 | angiogenesis |
| BP | IDA | GO:0006468 | protein phosphorylation |
| BP | IDA | GO:0008284 | positive regulation of cell proliferation |
| BP | IDA | GO:0008380 | RNA splicing |
| BP | IBA | GO:0010468 | regulation of gene expression |
| BP | ISS | GO:0010628 | positive regulation of gene expression |
| BP | IEA | GO:0030154 | cell differentiation |
| BP | ISS | GO:0035063 | nuclear speck organization |
| BP | IBA | GO:0035556 | intracellular signal transduction |
| BP | IDA | GO:0035556 | intracellular signal transduction |
| BP | ISS | GO:0043525 | positive regulation of neuron apoptotic process |
| BP | IDA | GO:0045070 | positive regulation of viral genome replication |
| BP | IDA | GO:0045071 | negative regulation of viral genome replication |
| BP | IC | GO:0045087 | innate immune response |
| BP | ISS | GO:0045787 | positive regulation of cell cycle |
| BP | TAS | GO:0048024 | regulation of mRNA splicing, via spliceosome |
| BP | IBA | GO:0050684 | regulation of mRNA processing |
| MF | IDA | GO:0000287 | magnesium ion binding |
| MF | HDA | GO:0003723 | RNA binding |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IDA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0005524 | ATP binding |
| MF | ISS | GO:0071889 | 14-3-3 protein binding |
Gene expression in normal tissue: SRPK2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD322 | FK 866 | 3 |
| iGMDRD82 | Quiflapon | 3 |
| iGMDRD147 | Prima-1 | 2 |
| iGMDRD505 | Pevonedistat | 2 |
| iGMDRD300 | Tozasertib | 3 |
| iGMDRD367 | Ro 28-1675 | 6 |
| iGMDRD414 | MST-312 | 4 |
| iGMDRD67 | PENFLURIDOL | 2 |
| iGMDRD286 | Nsc 632839 | 6 |
| iGMDRD221 | Tamoxifen | 3 |
| iGMDRD289 | Parthenolide | 2 |
| iGMDRD6 | AM-580 | 6 |
| iGMDRD121 | GMX1778 | 3 |
| iGMDRD137 | Indisulam | 3 |
| iGMDRD154 | NSC23766 | 4 |
| iGMDRD237 | ABT-751 | 2 |
| iGMDRD79 | Gemcitabine | 2 |
| iGMDRD512 | nutlin 3 | 2 |
| iGMDRD84 | Lovastatin acid | 3 |
| iGMDRD23 | Gossypol | 6 |
| iGMDRD356 | PNU-74654 | 3 |
| iGMDRD562 | Navitoclax | 3 |
| iGMDRD398 | Sepantronium | 2 |
| iGMDRD577 | BIX01294 | 5 |
| iGMDRD506 | Fedratinib | 2 |
| iGMDRD888 | Compound 44 | 3 |
| iGMDRD188 | Piperlongumine | 3 |
| iGMDRD441 | TW 37 | 1 |
| iGMDRD226 | ML006 | 3 |
| iGMDRD255 | SB225002 | 3 |
| iGMDRD513 | BML-259 | 2 |
| iGMDRD634 | SCHEMBL2608041 | 3 |
| iGMDRD466 | Chaetocin | 1 |
| iGMDRD280 | CYTOCHALASIN B | 3 |
| iGMDRD61 | Kinetin riboside | 2 |
| iGMDRD152 | 179324-69-7 | 2 |
| iGMDRD2 | PK-11195 | 3 |
| iGMDRD446 | LY 2183240 | 1 |
| iGMDRD781 | Sirolimus | 3 |
| iGMDRD427 | ABT737 | 1 |
| iGMDRD144 | NSC95397 | 1 |
| iGMDRD579 | PF750 | 3 |
| iGMDRD599 | Salermide | 2 |
| iGMDRD554 | CHEMBL1434137 | 3 |
| iGMDRD126 | Tipifarnib | 5 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SRPK2
CLASSFICATION
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