THRAP3


Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in THRAP3


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IMP GO:0000381 regulation of alternative mRNA splicing, via spliceosome
BP IDA GO:0000956 nuclear-transcribed mRNA catabolic process
BP IDA GO:0006367 transcription initiation from RNA polymerase II promoter
BP IEA GO:0006397 mRNA processing
BP IEA GO:0007623 circadian rhythm
BP IEA GO:0008380 RNA splicing
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Gene expression in normal tissue: THRAP3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined28PI3K/MTOR signaling2Apoptosis regulation2Protein stability and degradation1DNA replication1Cell cycle1Drug metabolism - cytochrome P4501Mitosis1Other, kinases1Longevity regulating pathway1

Pathways in THRAP3


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Database
Pathway ID
Pathway Des.
wikipathways WP2916 Interactome of polycomb repressive complex 2 (PRC2)
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1430728 Metabolism
reactome R-HSA-1989781 PPARA activates gene expression
reactome R-HSA-381340 Transcriptional regulation of white adipocyte differentiation
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD23 Gossypol 3
iGMDRD369 TGX-115 3
iGMDRD577 BIX01294 2
iGMDRD506 Fedratinib 4
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in THRAP3

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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