TTBK1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| tau tubulin kinase 1 | Ensembl:ENSG00000146216 | HGNC:HGNC:19140 | PA134866142 | 6p21.1 |
GO terms in TTBK1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IMP | GO:0006468 | protein phosphorylation |
| BP | IMP | GO:0007611 | learning or memory |
| BP | IMP | GO:0010628 | positive regulation of gene expression |
| BP | IMP | GO:0010629 | negative regulation of gene expression |
| BP | IBA | GO:0018105 | peptidyl-serine phosphorylation |
| BP | IDA | GO:0018105 | peptidyl-serine phosphorylation |
| BP | IDA | GO:0018107 | peptidyl-threonine phosphorylation |
| BP | IDA | GO:0018108 | peptidyl-tyrosine phosphorylation |
| BP | HEP | GO:0021762 | substantia nigra development |
| BP | IMP | GO:0032091 | negative regulation of protein binding |
| BP | IDA | GO:0032273 | positive regulation of protein polymerization |
| BP | IMP | GO:0061890 | positive regulation of astrocyte activation |
| BP | IMP | GO:1903980 | positive regulation of microglial cell activation |
| BP | IMP | GO:1904031 | positive regulation of cyclin-dependent protein kinase activity |
| BP | IMP | GO:2001056 | positive regulation of cysteine-type endopeptidase activity |
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005829 | cytosol |
| CC | IC | GO:0005875 | microtubule associated complex |
| CC | IDA | GO:0043025 | neuronal cell body |
| CC | ISS | GO:0048471 | perinuclear region of cytoplasm |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | NAS | GO:0004674 | protein serine/threonine kinase activity |
| MF | IEA | GO:0005524 | ATP binding |
Gene expression in normal tissue: TTBK1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD297 | Austocystin D | 6 |
| iGMDRD698 | Neratinib | 2 |
| iGMDRD237 | ABT-751 | 1 |
| iGMDRD152 | 179324-69-7 | 4 |
| iGMDRD61 | Kinetin riboside | 4 |
| iGMDRD446 | LY 2183240 | 4 |
| iGMDRD116 | CD437 | 2 |
| iGMDRD144 | NSC95397 | 5 |
| iGMDRD599 | Salermide | 2 |
| iGMDRD84 | Lovastatin acid | 2 |
| iGMDRD23 | Gossypol | 2 |
| iGMDRD322 | FK 866 | 2 |
| iGMDRD886 | Compound 1541A | 5 |
| iGMDRD263 | AACOCF3 | 1 |
| iGMDRD562 | Navitoclax | 5 |
| iGMDRD414 | MST-312 | 8 |
| iGMDRD67 | PENFLURIDOL | 2 |
| iGMDRD100 | Zebularine | 2 |
| iGMDRD286 | Nsc 632839 | 4 |
| iGMDRD188 | Piperlongumine | 4 |
| iGMDRD441 | TW 37 | 4 |
| iGMDRD870 | BRD63610 | 2 |
| iGMDRD6 | AM-580 | 4 |
| iGMDRD255 | SB225002 | 2 |
| iGMDRD513 | BML-259 | 4 |
| iGMDRD103 | SN-38 | 5 |
| iGMDRD121 | GMX1778 | 3 |
| iGMDRD251 | ML162 | 3 |
| iGMDRD202 | Curcumin | 3 |
| iGMDRD138 | PX 12 | 5 |
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in TTBK1

