TTBK1
Summary:
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
tau tubulin kinase 1 | Ensembl:ENSG00000146216 | HGNC:HGNC:19140 | PA134866142 | 6p21.1 |
GO terms in TTBK1
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IMP | GO:0006468 | protein phosphorylation |
BP | IMP | GO:0007611 | learning or memory |
BP | IMP | GO:0010628 | positive regulation of gene expression |
BP | IMP | GO:0010629 | negative regulation of gene expression |
BP | IBA | GO:0018105 | peptidyl-serine phosphorylation |
BP | IDA | GO:0018105 | peptidyl-serine phosphorylation |
BP | IDA | GO:0018107 | peptidyl-threonine phosphorylation |
BP | IDA | GO:0018108 | peptidyl-tyrosine phosphorylation |
BP | HEP | GO:0021762 | substantia nigra development |
BP | IMP | GO:0032091 | negative regulation of protein binding |
BP | IDA | GO:0032273 | positive regulation of protein polymerization |
BP | IMP | GO:0061890 | positive regulation of astrocyte activation |
BP | IMP | GO:1903980 | positive regulation of microglial cell activation |
BP | IMP | GO:1904031 | positive regulation of cyclin-dependent protein kinase activity |
BP | IMP | GO:2001056 | positive regulation of cysteine-type endopeptidase activity |
CC | IBA | GO:0005634 | nucleus |
CC | IDA | GO:0005654 | nucleoplasm |
CC | IBA | GO:0005737 | cytoplasm |
CC | IDA | GO:0005829 | cytosol |
CC | IC | GO:0005875 | microtubule associated complex |
CC | IDA | GO:0043025 | neuronal cell body |
CC | ISS | GO:0048471 | perinuclear region of cytoplasm |
MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
MF | NAS | GO:0004674 | protein serine/threonine kinase activity |
MF | IEA | GO:0005524 | ATP binding |
Gene expression in normal tissue: TTBK1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene-Drug: Aster Plot
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD297 | Austocystin D | 6 |
iGMDRD698 | Neratinib | 2 |
iGMDRD237 | ABT-751 | 1 |
iGMDRD152 | 179324-69-7 | 4 |
iGMDRD61 | Kinetin riboside | 4 |
iGMDRD446 | LY 2183240 | 4 |
iGMDRD116 | CD437 | 2 |
iGMDRD144 | NSC95397 | 5 |
iGMDRD599 | Salermide | 2 |
iGMDRD84 | Lovastatin acid | 2 |
iGMDRD23 | Gossypol | 2 |
iGMDRD322 | FK 866 | 2 |
iGMDRD886 | Compound 1541A | 5 |
iGMDRD263 | AACOCF3 | 1 |
iGMDRD562 | Navitoclax | 5 |
iGMDRD414 | MST-312 | 8 |
iGMDRD67 | PENFLURIDOL | 2 |
iGMDRD100 | Zebularine | 2 |
iGMDRD286 | Nsc 632839 | 4 |
iGMDRD188 | Piperlongumine | 4 |
iGMDRD441 | TW 37 | 4 |
iGMDRD870 | BRD63610 | 2 |
iGMDRD6 | AM-580 | 4 |
iGMDRD255 | SB225002 | 2 |
iGMDRD513 | BML-259 | 4 |
iGMDRD103 | SN-38 | 5 |
iGMDRD121 | GMX1778 | 3 |
iGMDRD251 | ML162 | 3 |
iGMDRD202 | Curcumin | 3 |
iGMDRD138 | PX 12 | 5 |
Gene in drug-gene network: Network Plot
![](image/gene_network_legends.png)
Gene-drug targets distribution
Gene Structure: PDB
Models in TTBK1