TTBK1


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
tau tubulin kinase 1Ensembl:ENSG00000146216HGNC:HGNC:19140PA1348661426p21.1

GO terms in TTBK1


Term TypeEvidence TypeGO Term IDGO Des.
BPIMPGO:0006468protein phosphorylation
BPIMPGO:0007611learning or memory
BPIMPGO:0010628positive regulation of gene expression
BPIMPGO:0010629negative regulation of gene expression
BPIBAGO:0018105peptidyl-serine phosphorylation
BPIDAGO:0018105peptidyl-serine phosphorylation
BPIDAGO:0018107peptidyl-threonine phosphorylation
BPIDAGO:0018108peptidyl-tyrosine phosphorylation
BPHEPGO:0021762substantia nigra development
BPIMPGO:0032091negative regulation of protein binding
BPIDAGO:0032273positive regulation of protein polymerization
BPIMPGO:0061890positive regulation of astrocyte activation
BPIMPGO:1903980positive regulation of microglial cell activation
BPIMPGO:1904031positive regulation of cyclin-dependent protein kinase activity
BPIMPGO:2001056positive regulation of cysteine-type endopeptidase activity
CCIBAGO:0005634nucleus
CCIDAGO:0005654nucleoplasm
CCIBAGO:0005737cytoplasm
CCIDAGO:0005829cytosol
CCICGO:0005875microtubule associated complex
CCIDAGO:0043025neuronal cell body
CCISSGO:0048471perinuclear region of cytoplasm
MFIBAGO:0004674protein serine/threonine kinase activity
MFNASGO:0004674protein serine/threonine kinase activity
MFIEAGO:0005524ATP binding

Gene expression in normal tissue: TTBK1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TTBK1


DatabasePathway IDPathway Des.
wikipathwaysWP4223Ras Signaling

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD297Austocystin D6
iGMDRD698Neratinib2
iGMDRD237ABT-7511
iGMDRD152179324-69-74
iGMDRD61Kinetin riboside4
iGMDRD446LY 21832404
iGMDRD116CD4372
iGMDRD144NSC953975
iGMDRD599Salermide2
iGMDRD84Lovastatin acid2
iGMDRD23Gossypol2
iGMDRD322FK 8662
iGMDRD886Compound 1541A5
iGMDRD263AACOCF31
iGMDRD562Navitoclax5
iGMDRD414MST-3128
iGMDRD67PENFLURIDOL2
iGMDRD100Zebularine2
iGMDRD286Nsc 6328394
iGMDRD188Piperlongumine4
iGMDRD441TW 374
iGMDRD870BRD636102
iGMDRD6AM-5804
iGMDRD255SB2250022
iGMDRD513BML-2594
iGMDRD103SN-385
iGMDRD121GMX17783
iGMDRD251ML1623
iGMDRD202Curcumin3
iGMDRD138PX 125

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TTBK1

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