ACOD1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| aconitate decarboxylase 1 | MIM:615275 | Ensembl:ENSG00000102794 | HGNC:HGNC:33904 | PA162392282 | 13q22.3 |
GO terms in ACOD1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0047547 | 2-methylcitrate dehydratase activity |
| MF | IBA | GO:0047613 | aconitate decarboxylase activity |
| MF | IDA | GO:0047613 | aconitate decarboxylase activity |
| CC | IBA | GO:0005739 | mitochondrion |
| CC | ISS | GO:0005739 | mitochondrion |
| BP | IDA | GO:0002760 | positive regulation of antimicrobial humoral response |
| BP | IBA | GO:0006952 | defense response |
| BP | IDA | GO:0006952 | defense response |
| BP | IEA | GO:0006954 | inflammatory response |
| BP | ISS | GO:0007566 | embryo implantation |
| BP | IBA | GO:0019679 | propionate metabolic process, methylcitrate cycle |
| BP | ISS | GO:0032088 | negative regulation of NF-kappaB transcription factor activity |
| BP | ISS | GO:0032480 | negative regulation of type I interferon production |
| BP | ISS | GO:0034136 | negative regulation of toll-like receptor 2 signaling pathway |
| BP | ISS | GO:0034144 | negative regulation of toll-like receptor 4 signaling pathway |
| BP | ISS | GO:0035458 | cellular response to interferon-beta |
| BP | ISS | GO:0045824 | negative regulation of innate immune response |
| BP | ISS | GO:0050728 | negative regulation of inflammatory response |
| BP | ISS | GO:0071219 | cellular response to molecule of bacterial origin |
| BP | IDA | GO:0071222 | cellular response to lipopolysaccharide |
| BP | ISS | GO:0071346 | cellular response to interferon-gamma |
| BP | ISS | GO:0071347 | cellular response to interleukin-1 |
| BP | ISS | GO:0071356 | cellular response to tumor necrosis factor |
| BP | ISS | GO:0071393 | cellular response to progesterone stimulus |
| BP | IDA | GO:0072573 | tolerance induction to lipopolysaccharide |
| BP | ISS | GO:2000379 | positive regulation of reactive oxygen species metabolic process |
Gene expression in normal tissue: ACOD1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ACOD1
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD150 | RITA | 3 |
| iGMDRD307 | Manumycin A | 3 |
| iGMDRD123 | Isoevodiamine | 4 |
| iGMDRD901 | ELCPK | 3 |
| iGMDRD237 | ABT-751 | 3 |
| iGMDRD351 | GW843682X | 3 |
| iGMDRD705 | Nakiterpiosin | 3 |
| iGMDRD481 | Dactolisib | 3 |
| iGMDRD158 | NSC141540 | 3 |
| iGMDRD202 | Curcumin | 6 |
| iGMDRD103 | SN-38 | 1 |
| iGMDRD246 | NPC26 | 3 |
| iGMDRD300 | Tozasertib | 6 |
| iGMDRD871 | BRD6368 | 3 |
| iGMDRD329 | Merck60 | 6 |
| iGMDRD144 | NSC95397 | 3 |
| iGMDRD781 | Sirolimus | 3 |
| iGMDRD433 | Lexibulin | 3 |
| iGMDRD151 | CHM-1 | 3 |
| iGMDRD126 | Tipifarnib | 3 |
| iGMDRD1008 | SR-II-138A | 3 |
| iGMDRD387 | CHIR-99021 | 1 |
| iGMDRD599 | Salermide | 3 |
| iGMDRD280 | CYTOCHALASIN B | 3 |
| iGMDRD297 | Austocystin D | 4 |
| iGMDRD446 | LY 2183240 | 6 |
| iGMDRD193 | Fqi1 | 3 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD187 | BRD9876 | 3 |
| iGMDRD138 | PX 12 | 3 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD74 | Idarubicin | 6 |
| iGMDRD188 | Piperlongumine | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ACOD1
CLASSFICATION
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