PKDCC
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| protein kinase domain containing, cytoplasmic | MIM:614150 | Ensembl:ENSG00000162878 | HGNC:HGNC:25123 | PA165697259 | 2p21 |
GO terms in PKDCC
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005576 | extracellular region |
| CC | ISS | GO:0005794 | Golgi apparatus |
| BP | IEA | GO:0001501 | skeletal system development |
| BP | IEA | GO:0015031 | protein transport |
| BP | IDA | GO:0018108 | peptidyl-tyrosine phosphorylation |
| BP | IEA | GO:0030154 | cell differentiation |
| BP | IEA | GO:0030282 | bone mineralization |
| BP | ISS | GO:0030501 | positive regulation of bone mineralization |
| BP | ISS | GO:0032332 | positive regulation of chondrocyte differentiation |
| BP | IEA | GO:0035108 | limb morphogenesis |
| BP | IEA | GO:0035264 | multicellular organism growth |
| BP | ISS | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport |
| BP | ISS | GO:0048286 | lung alveolus development |
| BP | ISS | GO:0048566 | embryonic digestive tract development |
| BP | ISS | GO:0060021 | roof of mouth development |
| MF | ISS | GO:0004672 | protein kinase activity |
| MF | IDA | GO:0004715 | non-membrane spanning protein tyrosine kinase activity |
| MF | IEA | GO:0005524 | ATP binding |
Gene expression in normal tissue: PKDCC
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PKDCC
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD297 | Austocystin D | 6 |
| iGMDRD679 | Bistramide A | 3 |
| iGMDRD85 | Ursolic acid | 3 |
| iGMDRD405 | PIK-75 | 3 |
| iGMDRD546 | BMS-754807 | 6 |
| iGMDRD424 | Tamatinib | 3 |
| iGMDRD599 | Salermide | 3 |
| iGMDRD772 | BRD4770 | 3 |
| iGMDRD554 | CHEMBL1434137 | 6 |
| iGMDRD23 | Gossypol | 3 |
| iGMDRD886 | Compound 1541A | 6 |
| iGMDRD577 | BIX01294 | 3 |
| iGMDRD506 | Fedratinib | 4 |
| iGMDRD888 | Compound 44 | 3 |
| iGMDRD562 | Navitoclax | 3 |
| iGMDRD780 | PP-30 | 3 |
| iGMDRD226 | ML006 | 3 |
| iGMDRD6 | AM-580 | 6 |
| iGMDRD513 | BML-259 | 1 |
| iGMDRD137 | Indisulam | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PKDCC
CLASSFICATION
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