ANKK1


Summary: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009].

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GO terms in ANKK1


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0006468 protein phosphorylation
MF IEA GO:0004674 protein serine/threonine kinase activity
MF IEA GO:0005524 ATP binding
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Gene expression in normal tissue: ANKK1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

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Pathways in ANKK1


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD158 NSC141540 1
iGMDRD705 Nakiterpiosin 3
iGMDRD289 Parthenolide 2
iGMDRD6 AM-580 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ANKK1

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Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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