SLC45A3
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| solute carrier family 45 member 3 | MIM:605097 | Ensembl:ENSG00000158715 | HGNC:HGNC:8642 | PA32981 | 1q32.1 |
GO terms in SLC45A3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| BP | TAS | GO:0008645 | hexose transmembrane transport |
| BP | ISS | GO:0010907 | positive regulation of glucose metabolic process |
| BP | ISS | GO:0015770 | sucrose transport |
| BP | ISS | GO:0045723 | positive regulation of fatty acid biosynthetic process |
| BP | ISS | GO:0048713 | regulation of oligodendrocyte differentiation |
| MF | ISS | GO:0008506 | sucrose:proton symporter activity |
| MF | TAS | GO:0051119 | sugar transmembrane transporter activity |
Gene expression in normal tissue: SLC45A3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SLC45A3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa05202 | Transcriptional misregulation in cancer - Homo sapiens (human) |
| kegg | hsa05206 | MicroRNAs in cancer - Homo sapiens (human) |
| reactome | R-HSA-189200 | Cellular hexose transport |
| reactome | R-HSA-382551 | Transport of small molecules |
| reactome | R-HSA-425407 | SLC-mediated transmembrane transport |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD138 | PX 12 | 3 |
| iGMDRD330 | BRD4132 | 1 |
| iGMDRD599 | Salermide | 6 |
| iGMDRD5 | Tyrphostin AG 1478 | 3 |
| iGMDRD144 | NSC95397 | 3 |
| iGMDRD188 | Piperlongumine | 6 |
| iGMDRD341 | Triacsin c | 3 |
| iGMDRD85 | Ursolic acid | 3 |
| iGMDRD329 | Merck60 | 3 |
| iGMDRD398 | Sepantronium | 3 |
| iGMDRD61 | Kinetin riboside | 3 |
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in SLC45A3

