GATA1
Summary: This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:305371 Ensembl IDEnsembl:ENSG00000102145 HGNC IDHGNC:HGNC:4170 PHARMGKB IDPA28584 Map LocationXp11.23 |
GO terms in GATA1
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IDA | GO:0000122 | negative regulation of transcription by RNA polymerase II |
BP | IEA | GO:0001701 | in utero embryonic development |
BP | IDA | GO:0006366 | transcription by RNA polymerase II |
BP | IEA | GO:0007267 | cell-cell signaling |
BP | IBA | GO:0007507 | heart development |
BP | TAS | GO:0007596 | blood coagulation |
Gene expression in normal tissue: GATA1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GATA1
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Database | Pathway ID | Pathway Des. |
---|---|---|
wikipathways | WP2849 | Hematopoietic Stem Cell Differentiation |
pid | cmyb_pathway | C-MYB transcription factor network |
pid | hdac_classi_pathway | Signaling events mediated by HDAC Class I |
pid | hdac_classii_pathway | Signaling events mediated by HDAC Class II |
pid | hes_heypathway | Notch-mediated HES/HEY network |
pid | p73pathway | p73 transcription factor network |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in GATA1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |