MTCL1
Summary:
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
microtubule crosslinking factor 1 | MIM:615766 | Ensembl:ENSG00000168502 | HGNC:HGNC:29121 | PA128394616 | 18p11.22 |
GO terms in MTCL1
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IBA | GO:0001578 | microtubule bundle formation |
BP | ISS | GO:0001578 | microtubule bundle formation |
BP | IEA | GO:0010506 | regulation of autophagy |
BP | IBA | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity |
BP | ISS | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity |
BP | ISS | GO:0090314 | positive regulation of protein targeting to membrane |
BP | ISS | GO:2000576 | positive regulation of microtubule motor activity |
CC | IBA | GO:0000922 | spindle pole |
CC | IDA | GO:0000922 | spindle pole |
CC | IEA | GO:0005615 | extracellular space |
CC | IEA | GO:0005737 | cytoplasm |
CC | IDA | GO:0005856 | cytoskeleton |
CC | IEA | GO:0016324 | apical plasma membrane |
CC | IBA | GO:0016327 | apicolateral plasma membrane |
CC | ISS | GO:0016327 | apicolateral plasma membrane |
CC | IBA | GO:0016328 | lateral plasma membrane |
CC | ISS | GO:0016328 | lateral plasma membrane |
CC | IBA | GO:0030496 | midbody |
CC | IDA | GO:0030496 | midbody |
CC | IBA | GO:0097427 | microtubule bundle |
CC | ISS | GO:0097427 | microtubule bundle |
MF | HDA | GO:0003723 | RNA binding |
MF | IBA | GO:0008017 | microtubule binding |
MF | IDA | GO:0008017 | microtubule binding |
MF | ISS | GO:0042803 | protein homodimerization activity |
Gene expression in normal tissue: MTCL1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MTCL1
Database | Pathway ID | Pathway Des. |
---|
Gene-Drug: Aster Plot
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD187 | BRD9876 | 2 |
iGMDRD52 | Rotenone | 2 |
iGMDRD138 | PX 12 | 2 |
iGMDRD474 | Avrainvillamide | 3 |
iGMDRD356 | PNU-74654 | 2 |
iGMDRD23 | Gossypol | 5 |
iGMDRD598 | QS-11 | 2 |
iGMDRD64 | Parbendazole | 3 |
iGMDRD369 | TGX-115 | 2 |
iGMDRD506 | Fedratinib | 2 |
iGMDRD730 | Kahalalide F | 2 |
iGMDRD781 | Sirolimus | 5 |
iGMDRD484 | Pluripotin | 2 |
iGMDRD427 | ABT737 | 4 |
iGMDRD599 | Salermide | 4 |
iGMDRD889 | Compound 7d-cis | 2 |
iGMDRD433 | Lexibulin | 1 |
iGMDRD375 | GW-405833 | 2 |
iGMDRD679 | Bistramide A | 4 |
iGMDRD280 | CYTOCHALASIN B | 5 |
iGMDRD639 | YK 4-279 | 2 |
iGMDRD316 | N9-Isopropyl-olomoucine | 2 |
iGMDRD193 | Fqi1 | 2 |
iGMDRD61 | Kinetin riboside | 3 |
iGMDRD446 | LY 2183240 | 5 |
iGMDRD267 | Oligomycin A | 1 |
iGMDRD6 | AM-580 | 2 |
iGMDRD434 | BMS-536924 | 2 |
iGMDRD5 | Tyrphostin AG 1478 | 2 |
iGMDRD103 | SN-38 | 2 |
iGMDRD158 | NSC141540 | 2 |
iGMDRD505 | Pevonedistat | 3 |
iGMDRD300 | Tozasertib | 6 |
iGMDRD246 | NPC26 | 2 |
iGMDRD414 | MST-312 | 3 |
iGMDRD882 | CIL41 | 1 |
iGMDRD701 | NVP-AUY922 | 2 |
iGMDRD560 | MK-2206 | 2 |
iGMDRD607 | Ubistatin B | 2 |
iGMDRD512 | nutlin 3 | 3 |
iGMDRD330 | BRD4132 | 4 |
iGMDRD945 | ML214 | 1 |
iGMDRD177 | Teniposide | 2 |
iGMDRD123 | Isoevodiamine | 4 |
iGMDRD314 | Tanespimycin | 2 |
iGMDRD351 | GW843682X | 1 |
iGMDRD237 | ABT-751 | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MTCL1