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iGMDRD598

Canonical SMILES: C1CC2=C(C1)C=C(C=C2)OC3=NC4=C(C(=N3)NC(CC5=CC=CC=C5)CO)N=CN4CC6=CC=C(C=C6)C7=CC=CC=C7

InChI: InChI=1S/C36H33N5O2/c42-23-31(20-25-8-3-1-4-9-25)38-34-33-35(40-36(39-34)43-32-19-18-28-12-7-13-30(28)21-32)41(24-37-33)22-26-14-16-29(17-15-26)27-10-5-2-6-11-27/h1-6,8-11,14-19,21,24,31,42H,7,12-13,20,22-23H2,(H,38,39,40)/t31-/m0/s1

InChI Key: DOKZLKDGUQWMSX-HKBQPEDESA-N

Standard Name	CHEMBL	Pubchem CID	Drug Status	Drug Type
QS-11	CHEMBL259181	42623900	Alone	Small Molecule

Drug Targets:

ARFGAP

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
64901	RANBP17	2
79848	CSPP1	3
5546	PRCC	3
57554	LRRC7	1
4750	NEK1	3
9475	ROCK2	2
56776	FMN2	2
5079	PAX5	3
9757	KMT2B	1
2043	EPHA4	3
9699	RIMS2	1
5596	MAPK4	3
1111	CHEK1	1
57670	KIAA1549	3
22806	IKZF3	3
23255	MTCL1	2
5984	RFC4	3
51804	SIX4	3
983	CDK1	1
92	ACVR2A	3
6709	SPTAN1	2
9472	AKAP6	1
9590	AKAP12	2
28996	HIPK2	3
5924	RASGRF2	3
3932	LCK	1
4869	NPM1	2
863	CBFA2T3	3
4437	MSH3	4
23373	CRTC1	3
5297	PI4KA	1
4609	MYC	2
90956	ADCK2	3
23532	PRAME	1
7030	TFE3	2
8888	MCM3AP	2
22843	PPM1E	3
6093	ROCK1	3
1719	DHFR	4
80216	ALPK1	3
23250	ATP11A	3
7124	TNF	3
7403	KDM6A	2

Gene in drug-gene network: Network Plot

Models in QS-11

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.