LRRC7
Summary:
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
leucine rich repeat containing 7 | MIM:614453 | Ensembl:ENSG00000033122 | HGNC:HGNC:18531 | PA134879588 | 1p31.1 |
GO terms in LRRC7
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IPI | GO:0005515 | protein binding |
MF | IBA | GO:0035255 | ionotropic glutamate receptor binding |
BP | IBA | GO:0007268 | chemical synaptic transmission |
BP | IBA | GO:0010976 | positive regulation of neuron projection development |
BP | IBA | GO:0043113 | receptor clustering |
BP | TAS | GO:0043312 | neutrophil degranulation |
BP | IBA | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity |
BP | IBA | GO:0097120 | receptor localization to synapse |
BP | IBA | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane |
BP | IBA | GO:0098968 | neurotransmitter receptor transport postsynaptic membrane to endosome |
CC | TAS | GO:0005576 | extracellular region |
CC | IBA | GO:0005911 | cell-cell junction |
CC | IBA | GO:0005913 | cell-cell adherens junction |
CC | IBA | GO:0008328 | ionotropic glutamate receptor complex |
CC | IBA | GO:0014069 | postsynaptic density |
CC | IEA | GO:0014069 | postsynaptic density |
CC | IBA | GO:0016323 | basolateral plasma membrane |
CC | IBA | GO:0030054 | cell junction |
CC | IEA | GO:0030054 | cell junction |
CC | TAS | GO:0035580 | specific granule lumen |
CC | IBA | GO:0043005 | neuron projection |
CC | IBA | GO:0043194 | axon initial segment |
CC | IBA | GO:0045202 | synapse |
CC | IBA | GO:0045211 | postsynaptic membrane |
CC | IEA | GO:0045211 | postsynaptic membrane |
CC | IBA | GO:0097060 | synaptic membrane |
Gene expression in normal tissue: LRRC7
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in LRRC7
Database | Pathway ID | Pathway Des. |
---|---|---|
reactome | R-HSA-168249 | Innate Immune System |
reactome | R-HSA-168256 | Immune System |
reactome | R-HSA-6798695 | Neutrophil degranulation |
Gene-Drug: Aster Plot
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD524 | ISX-9 | 3 |
iGMDRD23 | Gossypol | 7 |
iGMDRD598 | QS-11 | 1 |
iGMDRD60 | Quinoclamine | 4 |
iGMDRD64 | Parbendazole | 2 |
iGMDRD369 | TGX-115 | 3 |
iGMDRD562 | Navitoclax | 9 |
iGMDRD577 | BIX01294 | 4 |
iGMDRD801 | 2,4-dideoxy-DC-45-A2 | 2 |
iGMDRD441 | TW 37 | 1 |
iGMDRD782 | DC-45-A2 | 6 |
iGMDRD207 | Capsaicin | 1 |
iGMDRD255 | SB225002 | 7 |
iGMDRD138 | PX 12 | 2 |
iGMDRD679 | Bistramide A | 2 |
iGMDRD466 | Chaetocin | 3 |
iGMDRD394 | BX-795 | 3 |
iGMDRD193 | Fqi1 | 1 |
iGMDRD446 | LY 2183240 | 2 |
iGMDRD781 | Sirolimus | 7 |
iGMDRD427 | ABT737 | 7 |
iGMDRD779 | PRL-3 Inhibitor I | 6 |
iGMDRD1008 | SR-II-138A | 2 |
iGMDRD772 | BRD4770 | 6 |
iGMDRD889 | Compound 7d-cis | 4 |
iGMDRD387 | CHIR-99021 | 1 |
iGMDRD433 | Lexibulin | 2 |
iGMDRD151 | CHM-1 | 3 |
iGMDRD126 | Tipifarnib | 3 |
iGMDRD322 | FK 866 | 3 |
iGMDRD82 | Quiflapon | 3 |
iGMDRD246 | NPC26 | 2 |
iGMDRD300 | Tozasertib | 2 |
iGMDRD505 | Pevonedistat | 2 |
iGMDRD886 | Compound 1541A | 2 |
iGMDRD872 | BRD7137 | 4 |
iGMDRD882 | CIL41 | 2 |
iGMDRD286 | Nsc 632839 | 7 |
iGMDRD871 | BRD6368 | 2 |
iGMDRD77 | Itraconazole | 3 |
iGMDRD267 | Oligomycin A | 3 |
iGMDRD289 | Parthenolide | 3 |
iGMDRD105 | Triptolide | 1 |
iGMDRD121 | GMX1778 | 4 |
iGMDRD158 | NSC141540 | 3 |
iGMDRD103 | SN-38 | 2 |
iGMDRD132 | (-)-gallocatechin-3-O-gallate | 3 |
iGMDRD945 | ML214 | 3 |
iGMDRD177 | Teniposide | 3 |
iGMDRD901 | ELCPK | 1 |
iGMDRD698 | Neratinib | 2 |
iGMDRD341 | Triacsin c | 2 |
iGMDRD522 | ML-030 | 2 |
iGMDRD299 | ICL 670 | 2 |
iGMDRD150 | RITA | 3 |
iGMDRD116 | CD437 | 3 |
iGMDRD607 | Ubistatin B | 1 |
iGMDRD84 | Lovastatin acid | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in LRRC7