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iGMDRD299

Canonical SMILES: C1=CC(=C2NC(=C3C=CC=CC3=O)N(N2)C4=CC=C(C=C4)C(=O)O)C(=O)C=C1

InChI: InChI=1S/C21H15N3O4/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28/h1-12,22-23H,(H,27,28)/b19-15-,20-16+

InChI Key: FMSOAWSKCWYLBB-VBGLAJCLSA-N

Standard Name	CHEMBL	Pubchem CID	KEGG Drug ID	DRUGBANK ID	Drug Status	Drug Type
ICL 670	CHEMBL550348	5493380	D03669	DB01609	Alone	Small Molecule

Drug Class:

Acids, Carbocyclic Azoles Benzene Derivatives Carboxylic Acids Chelating Agents Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 Enzyme Inducers Heavy Metal Antagonists Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Hydrocarbons Hydrocarbons, Aromatic Hydrocarbons, Cyclic Iron Chelating Agents Sequestering Agents Specialty Uses of Chemicals

Drug Targets:

Iron

Drug Synonyms:

Deferasirox (JAN/USAN/INN)Exjade (TN)Jadenu (TN)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
8019	BRD3	2
57554	LRRC7	2
3845	KRAS	2
55215	FANCI	1
8266	UBL4A	1
7253	TSHR	1
9816	URB2	1
51199	NIN	1
7373	COL14A1	1
139378	ADGRG4	2
7158	TP53BP1	1
32	ACACB	1
238	ALK	2
65217	PCDH15	1
7486	WRN	1
8714	ABCC3	1
9472	AKAP6	3
2778	GNAS	3
8148	TAF15	1
1029	CDKN2A	2
25836	NIPBL	2
675	BRCA2	1
607	BCL9	1
1956	EGFR	4
673	BRAF	4
9509	ADAMTS2	2
1806	DPYD	3
8805	TRIM24	2
5291	PIK3CB	2
7248	TSC1	2
10111	RAD50	1
4193	MDM2	1
23112	TNRC6B	1
1795	DOCK3	3

Gene in drug-gene network: Network Plot

Models in ICL 670

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DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.