BRD3
Summary: This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| bromodomain containing 3 | MIM:601541 | Ensembl:ENSG00000169925 | HGNC:HGNC:1104 | PA25415 | 9q34.2 |
GO terms in BRD3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0003682 | chromatin binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0070577 | lysine-acetylated histone binding |
| CC | IEA | GO:0005634 | nucleus |
| BP | IEA | GO:0006325 | chromatin organization |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IDA | GO:0006357 | regulation of transcription by RNA polymerase II |
Gene expression in normal tissue: BRD3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in BRD3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP3295 | Chemical Compounds to monitor Proteins |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD188 | Piperlongumine | 1 |
| iGMDRD100 | Zebularine | 1 |
| iGMDRD23 | Gossypol | 6 |
| iGMDRD356 | PNU-74654 | 2 |
| iGMDRD451 | Serdemetan | 2 |
| iGMDRD60 | Quinoclamine | 5 |
| iGMDRD64 | Parbendazole | 1 |
| iGMDRD255 | SB225002 | 3 |
| iGMDRD138 | PX 12 | 2 |
| iGMDRD187 | BRD9876 | 2 |
| iGMDRD294 | Batimastat | 1 |
| iGMDRD193 | Fqi1 | 2 |
| iGMDRD61 | Kinetin riboside | 2 |
| iGMDRD375 | GW-405833 | 2 |
| iGMDRD280 | CYTOCHALASIN B | 2 |
| iGMDRD772 | BRD4770 | 1 |
| iGMDRD554 | CHEMBL1434137 | 3 |
| iGMDRD483 | SCH-529074 | 1 |
| iGMDRD781 | Sirolimus | 1 |
| iGMDRD670 | ML 210 | 1 |
| iGMDRD546 | BMS-754807 | 2 |
| iGMDRD366 | PI-103 | 1 |
| iGMDRD82 | Quiflapon | 3 |
| iGMDRD246 | NPC26 | 2 |
| iGMDRD271 | Brefeldin A | 2 |
| iGMDRD77 | Itraconazole | 3 |
| iGMDRD267 | Oligomycin A | 3 |
| iGMDRD221 | Tamoxifen | 3 |
| iGMDRD57 | Chloropentafluorobenzene | 2 |
| iGMDRD85 | Ursolic acid | 5 |
| iGMDRD211 | (1S,3R)-RSL3 | 2 |
| iGMDRD901 | ELCPK | 3 |
| iGMDRD177 | Teniposide | 2 |
| iGMDRD84 | Lovastatin acid | 1 |
| iGMDRD405 | PIK-75 | 2 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 2 |
| iGMDRD299 | ICL 670 | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in BRD3
CLASSFICATION
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