SIX4
Summary: This gene encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. [provided by RefSeq, May 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
NameSIX homeobox 4 OMIM IDMIM:606342 Ensembl IDEnsembl:ENSG00000100625 HGNC IDHGNC:HGNC:10890 PHARMGKB IDPA35790 Map Location14q23.1 | |||||
GO terms in SIX4
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0006366 | transcription by RNA polymerase II |
| BP | ISS | GO:0007519 | skeletal muscle tissue development |
| BP | IEA | GO:0008582 | regulation of synaptic growth at neuromuscular junction |
| BP | ISS | GO:0008584 | male gonad development |
| BP | TAS | GO:0009653 | anatomical structure morphogenesis |
| BP | ISS | GO:0030238 | male sex determination |
Gene expression in normal tissue: SIX4
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SIX4
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SIX4
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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