RPGRIP1


Summary: This gene encodes a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells. Mutations in this gene lead to autosomal recessive congenital blindness. [provided by RefSeq, Oct 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
RPGR interacting protein 1MIM:605446Ensembl:ENSG00000092200HGNC:HGNC:13436PA3465714q11.2

GO terms in RPGRIP1


Term TypeEvidence TypeGO Term IDGO Des.
CCIEAGO:0005930axoneme
CCISSGO:0032391photoreceptor connecting cilium
BPIEAGO:0007601visual perception
BPIEAGO:0042462eye photoreceptor cell development
BPIEAGO:0050896response to stimulus
BPIEAGO:0060041retina development in camera-type eye
BPIEAGO:0061351neural precursor cell proliferation
MFIPIGO:0005515protein binding

Gene expression in normal tissue: RPGRIP1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RPGRIP1


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD451Serdemetan3
iGMDRD64Parbendazole3
iGMDRD577BIX012943
iGMDRD100Zebularine2
iGMDRD188Piperlongumine3
iGMDRD730Kahalalide F3
iGMDRD8012,4-dideoxy-DC-45-A23
iGMDRD187BRD98761
iGMDRD255SB2250023
iGMDRD513BML-2591
iGMDRD138PX 123
iGMDRD280CYTOCHALASIN B3
iGMDRD639YK 4-2793
iGMDRD152179324-69-72
iGMDRD193Fqi13
iGMDRD163all trans Retinoic Acid3
iGMDRD144NSC953975
iGMDRD599Salermide2
iGMDRD772BRD47703
iGMDRD76Simvastatin2
iGMDRD554CHEMBL14341371
iGMDRD300Tozasertib3
iGMDRD246NPC263
iGMDRD329Merck603
iGMDRD662JQ-13
iGMDRD871BRD63682
iGMDRD286Nsc 6328393
iGMDRD213SMR0000686503
iGMDRD289Parthenolide2
iGMDRD705Nakiterpiosin3
iGMDRD883CIL55A3
iGMDRD945ML2143
iGMDRD154NSC237663
iGMDRD79Gemcitabine2
iGMDRD560MK-22061
iGMDRD345Compound 10b [PMID: 11504634]3
iGMDRD607Ubistatin B6
iGMDRD512nutlin 31
iGMDRD330BRD41323

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RPGRIP1

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