SIK2

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namesalt inducible kinase 2
OMIM IDMIM:608973
Ensembl IDEnsembl:ENSG00000170145
HGNC IDHGNC:HGNC:21680
PHARMGKB IDPA164725750
Map Location11q23.1

GO terms in SIK2


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0006468 protein phosphorylation
BP IDA GO:0006468 protein phosphorylation
BP IBA GO:0032007 negative regulation of TOR signaling
BP IBA GO:0035556 intracellular signal transduction
BP IDA GO:0035556 intracellular signal transduction
BP IBA GO:0042149 cellular response to glucose starvation
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Gene expression in normal tissue: SIK2

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined41IGFR signaling2Apoptosis regulation2PI3K/MTOR signaling2Other, kinases1ERK MAPK signaling1Biosynthesis of secondary metabolites1Chromatin histone acetylation1Ferroptosis1Mitosis1

Pathways in SIK2


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Database
Pathway ID
Pathway Des.
kegg hsa04922 Glucagon signaling pathway - Homo sapiens (human)
pid lkb1_pathway LKB1 signaling events
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD123 Isoevodiamine 3
iGMDRD211 (1S,3R)-RSL3 5
iGMDRD945 ML214 3
iGMDRD424 Tamatinib 6
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SIK2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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