NPAP1


Summary: This gene is located in the Prader-Willi syndrome region on chromosome 15. This gene is biallelically expressed in adult testis and brain but is paternally imprinted in fetal brain. Defects in this gene may be associated with Prader-Willi syndrome. [provided by RefSeq, Aug 2012].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
nuclear pore associated protein 1MIM:610922Ensembl:ENSG00000185823HGNC:HGNC:1190PA2551915q11.2

Gene Categories:

TRANSPORTER

GO terms in NPAP1


Term TypeEvidence TypeGO Term IDGO Des.
MFNDGO:0003674molecular_function
MFIBAGO:0008139nuclear localization sequence binding
MFIBAGO:0017056structural constituent of nuclear pore
CCIEAGO:0005637nuclear inner membrane
CCIBAGO:0005643nuclear pore
CCIEAGO:0005654nucleoplasm
CCIBAGO:0044613nuclear pore central transport channel
CCIBAGO:0044615nuclear pore nuclear basket
BPIBAGO:0006405RNA export from nucleus
BPIBAGO:0006606protein import into nucleus
BPIEAGO:0007275multicellular organism development
BPNASGO:0007283spermatogenesis
BPIEAGO:0030154cell differentiation

Gene expression in normal tissue: NPAP1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in NPAP1


DatabasePathway IDPathway Des.
wikipathwaysWP3998Prader-Willi and Angelman Syndrome

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD562Navitoclax4
iGMDRD441TW 372
iGMDRD52Rotenone2
iGMDRD138PX 123
iGMDRD474Avrainvillamide2
iGMDRD280CYTOCHALASIN B3
iGMDRD2PK-111951
iGMDRD152179324-69-75
iGMDRD494Neopeltolide3
iGMDRD144NSC953978
iGMDRD427ABT7377
iGMDRD599Salermide2
iGMDRD420Leucascandrolide A2
iGMDRD42Vorinostat6
iGMDRD505Pevonedistat1
iGMDRD552AZD-17753
iGMDRD286Nsc 6328392
iGMDRD367Ro 28-16752
iGMDRD67PENFLURIDOL3
iGMDRD6AM-5802
iGMDRD289Parthenolide2
iGMDRD221Tamoxifen2
iGMDRD434BMS-5369242
iGMDRD121GMX17782
iGMDRD251ML1623
iGMDRD945ML2141
iGMDRD154NSC237666
iGMDRD511CHEMBL3993793
iGMDRD901ELCPK2
iGMDRD698Neratinib3
iGMDRD49Mitomycin3
iGMDRD523Cyanoquinoline, 112
iGMDRD150RITA3
iGMDRD330BRD41322

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in NPAP1

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