iGMDRD372

Canonical SMILES: CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4

InChI: InChI=1S/C21H24N4O2/c1-15-12-18(16(2)22-17-6-4-3-5-7-17)21-23-19(13-20(26)25(21)14-15)24-8-10-27-11-9-24/h3-7,12-14,16,22H,8-11H2,1-2H3

InChI Key: CPRAGQJXBLMUEL-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDrug StatusDrug Type
TGX 221CHEMBL1972466 9907090AloneSmall Molecule

Drug Targets:

PI3Kbeta

Drug Pathways:

PI3K/MTOR signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
2064ERBB21
27332ZNF6381
6794STK111
7422VEGFA1
23269MGA1
1956EGFR1
5728PTEN1
1493CTLA41
7520XRCC51
3265HRAS1
4780NFE2L21

Gene in drug-gene network: Network Plot

Models in TGX 221

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