iGMDRD450

Canonical SMILES: C1=CC=C2C(=C1)C(=CN2)CCNC3=CC=C(C=C3)NC4=CC=NC=C4

InChI: InChI=1S/C21H20N4/c1-2-4-21-20(3-1)16(15-24-21)9-14-23-17-5-7-18(8-6-17)25-19-10-12-22-13-11-19/h1-8,10-13,15,23-24H,9,14H2,(H,22,25)

InChI Key: CEGSUKYESLWKJP-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
JNJ-26854165CHEMBL2137530 11609600DB12027AloneSmall Molecule


Drug Targets:

MDM2

Drug Pathways:

p53 pathway

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
25937WWTR11
7428VHL1
6850SYK1
3932LCK1
7157TP531
6714SRC1
3791KDR1
23269MGA1
6280S100A91
1956EGFR1
8682PEA151
1977EIF4E1
1869E2F11
387RHOA1
54474KRT201
5111PCNA1
100862685ERVK-191
5054SERPINE11

Gene in drug-gene network: Network Plot

Models in JNJ-26854165

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