CLK3
Summary: This gene encodes a protein belonging to the serine/threonine type protein kinase family. This protein is a nuclear dual-specificity kinase that regulates the intranuclear distribution of the serine/arginine-rich (SR) family of splicing factors. Two transcript variants encoding different isoforms have been found for this gene. Related pseudogenes are located on chromosomes 1 and 9. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:602990 Ensembl IDEnsembl:ENSG00000179335 HGNC IDHGNC:HGNC:2071 PHARMGKB IDPA26597 Map Location15q24.1 | |||||
GO terms in CLK3
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IDA | GO:0006468 | protein phosphorylation |
| BP | IEA | GO:0018108 | peptidyl-tyrosine phosphorylation |
| BP | IDA | GO:0043484 | regulation of RNA splicing |
| BP | IEA | GO:0046777 | protein autophosphorylation |
| CC | IEA | GO:0001669 | acrosomal vesicle |
| CC | IDA | GO:0005634 | nucleus |
Gene expression in normal tissue: CLK3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CLK3
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP411 | mRNA Processing |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CLK3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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