TAL2

Summary: This intronless gene encodes a helix-loop-helix protein. Translocations between this gene on chromosome 9 and the T-cell receptor beta-chain locus on chromosome 7 have been associated with activation of the T-cell acute lymphocytic leukemia 2 gene and T-cell acute lymphoblastic leukemia. [provided by RefSeq, Mar 2009].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameTAL bHLH transcription factor 2
OMIM IDMIM:186855
Ensembl IDEnsembl:ENSG00000186051
HGNC IDHGNC:HGNC:11557
PHARMGKB IDPA36327
Map Location9q31.2

GO terms in TAL2


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0005634 nucleus
BP IEA GO:0006351 transcription, DNA-templated
BP IBA GO:0006357 regulation of transcription by RNA polymerase II
BP IEA GO:0006357 regulation of transcription by RNA polymerase II
BP IEA GO:0009791 post-embryonic development
BP IEA GO:0021794 thalamus development
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Gene expression in normal tissue: TAL2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined11Protein stability and degradation1p53 pathway1Leukocyte transendothelial migration1One carbon pool by folate1DNA replication1

Pathways in TAL2


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD171 Pemetrexed 1
iGMDRD801 2,4-dideoxy-DC-45-A2 3
iGMDRD187 BRD9876 2
iGMDRD294 Batimastat 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TAL2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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