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PRKACG

Summary: Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008].

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Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
Nameprotein kinase cAMP-activated catalytic subunit gamma OMIM IDMIM:176893 Ensembl IDEnsembl:ENSG00000165059 HGNC IDHGNC:HGNC:9382 PHARMGKB IDPA33750 Map Location9q21.11

Gene Categories:

DRUGGABLE GENOME KINASE SERINE THREONINE KINASE

GO terms in PRKACG

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Term Type	Evidence Type	GO Term ID	GO Des.
CC	TAS	GO:0005654	nucleoplasm
CC	IDA	GO:0005829	cytosol
CC	TAS	GO:0005829	cytosol
CC	IDA	GO:0045171	intercellular bridge
CC	TAS	GO:0097546	ciliary base
BP	TAS	GO:0002223	stimulatory C-type lectin receptor signaling pathway

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Gene expression in normal tissue: PRKACG

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PRKACG

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Database	Pathway ID	Pathway Des.
biocarta	agpcrpathway	attenuation of gpcr signaling
biocarta	akap13pathway	rho-selective guanine exchange factor akap13 mediates stress fiber formation
biocarta	akap95pathway	akap95 role in mitosis and chromosome dynamics
biocarta	akapcentrosomepathway	protein kinase a at the centrosome
biocarta	badpathway	regulation of bad phosphorylation
biocarta	carm1pathway	transcription regulation by methyltransferase of carm1

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Gene-Drug: Aster Plot

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Drug ID	Drug Name	Model Num.
iGMDRD152	179324-69-7	2
iGMDRD61	Kinetin riboside	6
iGMDRD201	SKI II	1
iGMDRD634	SCHEMBL2608041	3

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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PRKACG

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	Model	Level	Reference ID	Tissue	Cancer	Drug	Clinical Response	Source
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