CCL4

Summary: The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameC-C motif chemokine ligand 4
OMIM IDMIM:182284
Ensembl IDEnsembl:ENSG00000275302
HGNC IDHGNC:HGNC:10630
PHARMGKB IDPA35562
Map Location17q12

GO terms in CCL4


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0002548 monocyte chemotaxis
BP IBA GO:0006954 inflammatory response
BP TAS GO:0006955 immune response
BP TAS GO:0007155 cell adhesion
BP TAS GO:0007163 establishment or maintenance of cell polarity
BP TAS GO:0007165 signal transduction
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Gene expression in normal tissue: CCL4

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 40BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 18OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 8

Gene-drug pathway distribution

undefined18Cell cycle2One carbon pool by folate1DNA replication1p53 pathway1Protein stability and degradation1Leukocyte transendothelial migration1

Pathways in CCL4


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Database
Pathway ID
Pathway Des.
wikipathways WP1449 Regulation of toll-like receptor signaling pathway
wikipathways WP3624 Lung fibrosis
wikipathways WP3929 Chemokine signaling pathway
wikipathways WP4063 Interleukin-10 signaling
wikipathways WP75 Toll-like Receptor Signaling Pathway
netpath Pathway_BCR BCR
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD154 NSC23766 6
iGMDRD435 BI-2536 4
iGMDRD375 GW-405833 5
iGMDRD177 Teniposide 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CCL4

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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