ADGRB3
Summary: This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:602684 Ensembl IDEnsembl:ENSG00000135298 HGNC IDHGNC:HGNC:945 PHARMGKB IDPA25249 Map Location6q12-q13 | |||||
Gene Categories:
G PROTEIN COUPLED RECEPTORGO terms in ADGRB3
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0001965 | G-protein alpha-subunit binding |
| MF | IBA | GO:0004930 | G-protein coupled receptor activity |
| MF | IEA | GO:0004930 | G-protein coupled receptor activity |
| MF | ISS | GO:0005096 | GTPase activator activity |
| MF | IPI | GO:0005515 | protein binding |
| CC | IPI | GO:0005886 | plasma membrane |
Gene expression in normal tissue: ADGRB3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ADGRB3
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ADGRB3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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