MKRN3
Summary: The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:603856 Ensembl IDEnsembl:ENSG00000179455 HGNC IDHGNC:HGNC:7114 PHARMGKB IDPA30833 Map Location15q11.2 | |||||
GO terms in MKRN3
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:1990904 | ribonucleoprotein complex |
| BP | IEA | GO:0016567 | protein ubiquitination |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0016740 | transferase activity |
| MF | IPI | GO:0042802 | identical protein binding |
| MF | IEA | GO:0046872 | metal ion binding |
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Gene expression in normal tissue: MKRN3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MKRN3
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP3998 | Prader-Willi and Angelman Syndrome |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MKRN3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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