NRK

Summary: The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameNik related kinase
OMIM IDMIM:300791
Ensembl IDEnsembl:ENSG00000123572
HGNC IDHGNC:HGNC:25391
PHARMGKB IDPA134869113
Map LocationXq22.3

GO terms in NRK


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0004674 protein serine/threonine kinase activity
MF IEA GO:0005524 ATP binding
CC IBA GO:0005737 cytoplasm
BP IBA GO:0000165 MAPK cascade
BP IEA GO:0000185 activation of MAPKKK activity
BP IEA GO:0007256 activation of JNKK activity
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Gene expression in normal tissue: NRK

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in NRK


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Database
Pathway ID
Pathway Des.
wikipathways WP3644 NAD+ metabolism
pid tnfpathway TNF receptor signaling pathway
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD85 Ursolic acid 1
iGMDRD718 Pyrvinium pamoate 1
iGMDRD499 PDMP 2
iGMDRD314 Tanespimycin 5
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in NRK

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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