RAP1GDS1
Summary: The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).[supplied by OMIM, Feb 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:179502 Ensembl IDEnsembl:ENSG00000138698 HGNC IDHGNC:HGNC:9859 PHARMGKB IDPA34221 Map Location4q23 | |||||
GO terms in RAP1GDS1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | NAS | GO:0005096 | GTPase activator activity |
| MF | IPI | GO:0005515 | protein binding |
| BP | IBA | GO:0007264 | small GTPase mediated signal transduction |
| BP | IEA | GO:0014829 | vascular smooth muscle contraction |
| BP | IEA | GO:0031034 | myosin filament assembly |
| BP | IMP | GO:0032471 | negative regulation of endoplasmic reticulum calcium ion concentration |
Gene expression in normal tissue: RAP1GDS1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RAP1GDS1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| pid | rac1_reg_pathway | Regulation of RAC1 activity |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RAP1GDS1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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