TMEM74
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| transmembrane protein 74 | MIM:613935 | Ensembl:ENSG00000164841 | HGNC:HGNC:26409 | PA142670785 | 8q23.1 |
GO terms in TMEM74
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0000421 | autophagosome membrane |
| CC | IEA | GO:0005765 | lysosomal membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IEA | GO:0031410 | cytoplasmic vesicle |
| BP | IMP | GO:0016236 | macroautophagy |
| MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: TMEM74
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TMEM74
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD158 | NSC141540 | 11 |
| iGMDRD138 | PX 12 | 4 |
| iGMDRD137 | Indisulam | 3 |
| iGMDRD171 | Pemetrexed | 1 |
| iGMDRD289 | Parthenolide | 3 |
| iGMDRD187 | BRD9876 | 4 |
| iGMDRD801 | 2,4-dideoxy-DC-45-A2 | 8 |
| iGMDRD872 | BRD7137 | 4 |
| iGMDRD74 | Idarubicin | 2 |
| iGMDRD188 | Piperlongumine | 3 |
| iGMDRD871 | BRD6368 | 8 |
| iGMDRD147 | Prima-1 | 2 |
| iGMDRD690 | PRIMA-1MET | 8 |
| iGMDRD524 | ISX-9 | 3 |
| iGMDRD451 | Serdemetan | 3 |
| iGMDRD554 | CHEMBL1434137 | 3 |
| iGMDRD307 | Manumycin A | 8 |
| iGMDRD1008 | SR-II-138A | 3 |
| iGMDRD889 | Compound 7d-cis | 8 |
| iGMDRD546 | BMS-754807 | 3 |
| iGMDRD532 | Olaparib | 4 |
| iGMDRD79 | Gemcitabine | 4 |
| iGMDRD201 | SKI II | 1 |
| iGMDRD314 | Tanespimycin | 2 |
| iGMDRD177 | Teniposide | 4 |
| iGMDRD123 | Isoevodiamine | 1 |
| iGMDRD901 | ELCPK | 4 |
| iGMDRD154 | NSC23766 | 6 |
| iGMDRD375 | GW-405833 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TMEM74
CLASSFICATION
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