MPPED2
Summary: This gene likely encodes a metallophosphoesterase. The encoded protein may play a role a brain development. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| metallophosphoesterase domain containing 2 | MIM:600911 | Ensembl:ENSG00000066382 | HGNC:HGNC:1180 | PA25499 | 11p14.1 |
GO terms in MPPED2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0016787 | hydrolase activity |
| MF | IEA | GO:0046872 | metal ion binding |
| BP | TAS | GO:0007399 | nervous system development |
Gene expression in normal tissue: MPPED2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MPPED2
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD434 | BMS-536924 | 1 |
| iGMDRD801 | 2,4-dideoxy-DC-45-A2 | 2 |
| iGMDRD52 | Rotenone | 1 |
| iGMDRD267 | Oligomycin A | 4 |
| iGMDRD870 | BRD63610 | 2 |
| iGMDRD103 | SN-38 | 5 |
| iGMDRD60 | Quinoclamine | 3 |
| iGMDRD246 | NPC26 | 3 |
| iGMDRD353 | PD0325901 | 1 |
| iGMDRD23 | Gossypol | 2 |
| iGMDRD662 | JQ-1 | 3 |
| iGMDRD562 | Navitoclax | 5 |
| iGMDRD779 | PRL-3 Inhibitor I | 3 |
| iGMDRD427 | ABT737 | 2 |
| iGMDRD670 | ML 210 | 3 |
| iGMDRD523 | Cyanoquinoline, 11 | 1 |
| iGMDRD781 | Sirolimus | 3 |
| iGMDRD84 | Lovastatin acid | 2 |
| iGMDRD433 | Lexibulin | 3 |
| iGMDRD229 | B02 | 1 |
| iGMDRD248 | BRD4354 | 1 |
| iGMDRD148 | Pifithrin-mu | 3 |
| iGMDRD211 | (1S,3R)-RSL3 | 3 |
| iGMDRD394 | BX-795 | 3 |
| iGMDRD154 | NSC23766 | 2 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 2 |
| iGMDRD797 | ISOX DUAL | 3 |
| iGMDRD314 | Tanespimycin | 2 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD748 | PHA-665752 | 1 |
| iGMDRD219 | Bax channel blocker | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MPPED2
CLASSFICATION
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