MAST2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| microtubule associated serine/threonine kinase 2 | MIM:612257 | Ensembl:ENSG00000086015 | HGNC:HGNC:19035 | PA134954073 | 1p34.1 |
GO terms in MAST2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ISS | GO:0000287 | magnesium ion binding |
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | ISS | GO:0005524 | ATP binding |
| MF | IBA | GO:0008017 | microtubule binding |
| MF | IPI | GO:0019902 | phosphatase binding |
| BP | ISS | GO:0006468 | protein phosphorylation |
| BP | IBA | GO:0007010 | cytoskeleton organization |
| BP | IBA | GO:0018105 | peptidyl-serine phosphorylation |
| BP | IBA | GO:0035556 | intracellular signal transduction |
| BP | ISS | GO:0045075 | regulation of interleukin-12 biosynthetic process |
| BP | ISS | GO:0048515 | spermatid differentiation |
| CC | IEA | GO:0005737 | cytoplasm |
| CC | IEA | GO:0005886 | plasma membrane |
| CC | IBA | GO:0015630 | microtubule cytoskeleton |
Gene expression in normal tissue: MAST2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MAST2
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD171 | Pemetrexed | 2 |
| iGMDRD885 | Compound 110 | 2 |
| iGMDRD260 | FQI-2 | 2 |
| iGMDRD613 | CHEMBL258148 | 3 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD60 | Quinoclamine | 2 |
| iGMDRD451 | Serdemetan | 2 |
| iGMDRD399 | Selumetinib | 1 |
| iGMDRD188 | Piperlongumine | 4 |
| iGMDRD577 | BIX01294 | 7 |
| iGMDRD506 | Fedratinib | 4 |
| iGMDRD144 | NSC95397 | 3 |
| iGMDRD779 | PRL-3 Inhibitor I | 3 |
| iGMDRD546 | BMS-754807 | 3 |
| iGMDRD483 | SCH-529074 | 1 |
| iGMDRD151 | CHM-1 | 5 |
| iGMDRD1008 | SR-II-138A | 5 |
| iGMDRD387 | CHIR-99021 | 1 |
| iGMDRD466 | Chaetocin | 2 |
| iGMDRD193 | Fqi1 | 3 |
| iGMDRD221 | Tamoxifen | 3 |
| iGMDRD77 | Itraconazole | 2 |
| iGMDRD158 | NSC141540 | 1 |
| iGMDRD246 | NPC26 | 1 |
| iGMDRD300 | Tozasertib | 3 |
| iGMDRD82 | Quiflapon | 1 |
| iGMDRD286 | Nsc 632839 | 4 |
| iGMDRD366 | PI-103 | 2 |
| iGMDRD424 | Tamatinib | 3 |
| iGMDRD150 | RITA | 2 |
| iGMDRD583 | LDN 193189 | 2 |
| iGMDRD148 | Pifithrin-mu | 3 |
| iGMDRD512 | nutlin 3 | 4 |
| iGMDRD123 | Isoevodiamine | 3 |
| iGMDRD314 | Tanespimycin | 1 |
| iGMDRD698 | Neratinib | 6 |
| iGMDRD351 | GW843682X | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MAST2
CLASSFICATION
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