SRPK3

Summary: This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameSRSF protein kinase 3
OMIM IDMIM:301002
Ensembl IDEnsembl:ENSG00000184343
HGNC IDHGNC:HGNC:11402
PHARMGKB IDPA162404805
Map LocationXq28

GO terms in SRPK3


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0004674 protein serine/threonine kinase activity
MF IPI GO:0005515 protein binding
MF IEA GO:0005524 ATP binding
CC ND GO:0005575 cellular_component
CC IBA GO:0005634 nucleus
CC IBA GO:0005737 cytoplasm
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Gene expression in normal tissue: SRPK3

Gene-model tissue-cancer distribution: Bubble Plot

BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 8LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 3undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: ADENOCARCINOMA model num: 3undefinedtissue: undefined cancer: PANCAN model num: 23UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: Endometrial Carcinoma (UCEC) model num: 12BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: undefined model num: 3

Gene-drug pathway distribution

undefined12Apoptosis regulation1p53 pathway1Mitosis1DNA replication1Protein stability and degradation1Neuroactive ligand-receptor interaction1Longevity regulating pathway1Proteasome1

Pathways in SRPK3


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD148 Pifithrin-mu 1
iGMDRD512 nutlin 3 3
iGMDRD48 Dexamethasone 3
iGMDRD781 Sirolimus 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SRPK3

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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