RPS6KA5

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameribosomal protein S6 kinase A5
OMIM IDMIM:603607
Ensembl IDEnsembl:ENSG00000100784
HGNC IDHGNC:HGNC:10434
PHARMGKB IDPA34849
Map Location14q32.11

GO terms in RPS6KA5


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0000287 magnesium ion binding
MF IDA GO:0004672 protein kinase activity
MF EXP GO:0004674 protein serine/threonine kinase activity
MF IBA GO:0004674 protein serine/threonine kinase activity
MF IDA GO:0004674 protein serine/threonine kinase activity
MF IMP GO:0004674 protein serine/threonine kinase activity
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Gene expression in normal tissue: RPS6KA5

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 37undefinedtissue: undefined cancer: SMALL_CELL_CARCINOMA model num: 15BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 12LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 12

Gene-drug pathway distribution

undefined19Other, kinases1Apoptosis regulation1Mitosis1p53 pathway1Biosynthesis of secondary metabolites1DNA replication1WNT signaling1Longevity regulating pathway1Protein stability and degradation1

Pathways in RPS6KA5


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1280215 Cytokine Signaling in Immune system
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade
reactome R-HSA-166058 MyD88:Mal cascade initiated on plasma membrane
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD512 nutlin 3 3
iGMDRD387 CHIR-99021 2
iGMDRD889 Compound 7d-cis 3
iGMDRD483 SCH-529074 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RPS6KA5

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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