TEX14

Summary: The protein encoded by this gene is necessary for intercellular bridges in germ cells, which are required for spermatogenesis. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nametestis expressed 14, intercellular bridge forming factor
OMIM IDMIM:605792
Ensembl IDEnsembl:ENSG00000121101
HGNC IDHGNC:HGNC:11737
PHARMGKB IDPA36454
Map Location17q22

GO terms in TEX14


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0004672 protein kinase activity
MF IPI GO:0005515 protein binding
MF IEA GO:0005524 ATP binding
MF IPI GO:0019901 protein kinase binding
BP IEA GO:0006468 protein phosphorylation
BP IBA GO:0007094 mitotic spindle assembly checkpoint
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Gene expression in normal tissue: TEX14

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined26Apoptosis regulation2ERK MAPK signaling1Biosynthesis of secondary metabolites1IGFR signaling1Longevity regulating pathway1Protein stability and degradation1Mitosis1DNA replication1Cell cycle1

Pathways in TEX14


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD322 FK 866 4
iGMDRD82 Quiflapon 2
iGMDRD505 Pevonedistat 3
iGMDRD300 Tozasertib 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TEX14

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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