MARK1

Summary:

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namemicrotubule affinity regulating kinase 1
OMIM IDMIM:606511
Ensembl IDEnsembl:ENSG00000116141
HGNC IDHGNC:HGNC:6896
PHARMGKB IDPA30639
Map Location1q41

GO terms in MARK1


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0000226 microtubule cytoskeleton organization
BP ISS GO:0000226 microtubule cytoskeleton organization
BP ISS GO:0001764 neuron migration
BP IDA GO:0006468 protein phosphorylation
BP IMP GO:0006468 protein phosphorylation
BP ISS GO:0007010 cytoskeleton organization
Showing 1 to 6 of 32 rows rows per page

Gene expression in normal tissue: MARK1

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: SMALL_CELL_CARCINOMA model num: 12undefinedtissue: undefined cancer: PANCAN model num: 32undefinedtissue: undefined cancer: ADENOCARCINOMA model num: 3LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 15BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 16BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: undefined model num: 12UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: Endometrial Carcinoma (UCEC) model num: 6

Gene-drug pathway distribution

undefined28WNT signaling1ERK MAPK signaling1Other, kinases1PI3K/MTOR signaling1

Pathways in MARK1


Loading, please wait...
Database
Pathway ID
Pathway Des.
wikipathways WP2038 Regulation of Microtubule Cytoskeleton
Showing 1 to 1 of 1 rows

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD505 Pevonedistat 3
iGMDRD269 Purmorphamine 2
iGMDRD286 Nsc 632839 2
iGMDRD871 BRD6368 2
Showing 1 to 4 of 32 rows rows per page

Gene in drug-gene network: Network Plot

ADAMTS20ADAMTS20OBSCNOBSCNVAV1VAV1EGFREGFRSTAT5ASTAT5ATBCKTBCKRORARORALATS1LATS1CLSTN1CLSTN1CHD8CHD8HDAC8HDAC8PevonedistatPevonedistatSIK2SIK2POU2AF1POU2AF1TNFRSF4TNFRSF4PurmorphaminePurmorphamineRASA3RASA3RARARARAFGFR1FGFR1PCDH15PCDH15MLH1MLH1RPS6KA3RPS6KA3P4HBP4HBYWHAQYWHAQADHFE1ADHFE1TOP2ATOP2ANsc 632839Nsc 632839ABCA3ABCA3ADKADKTTKTTKFGF4FGF4CREBBPCREBBPADGRG4ADGRG4TMEM74TMEM74PKMYT1PKMYT1MAP4K2MAP4K2ERN1ERN1RICTORRICTORPRKG1PRKG1PIGUPIGUKSR2KSR2PIK3C2GPIK3C2GBRD6368BRD6368SERPINB4SERPINB4N4BP2N4BP2HIF1AHIF1AITGAVITGAVANAPC5ANAPC5PTK6PTK6BRAFBRAFCDC5LCDC5LPTENPTENCACNA1FCACNA1FSTK24STK24ERCC6ERCC6JAK1JAK1ZNF331ZNF331DAPK1DAPK1ACVRL1ACVRL1GRIA3GRIA3ImportazoleImportazolePHKG2PHKG2TSHRTSHRADAM18ADAM18COL4A3BPCOL4A3BPTBX18TBX18TEKTEKRPS6KL1RPS6KL1STK39STK39MCM4MCM4THRAP3THRAP3MAP4K4MAP4K4MAP3K1MAP3K1NCOA3NCOA3MYCMYCMYO3AMYO3ALRP1BLRP1BPRDM16PRDM16PRKD1PRKD1EHBP1EHBP1TSSK3TSSK3ItraconazoleItraconazoleCHEK1CHEK1CLTCL1CLTCL1GSK3AGSK3ADBN1DBN1ITGA7ITGA7NSC23766NSC23766NKX2-1NKX2-1TENM1TENM1KAT6BKAT6BMLLT3MLLT3FHITFHITSTK11STK11PTCH1PTCH1DBF4DBF4NFKB2NFKB2KMT2AKMT2AMYH10MYH10MBIPMBIPASPHASPHBax channel blockerBax channel blockerAFDNAFDNNLRP3NLRP3USP6USP6TGTGLDLRLDLRTFE3TFE3MTUS2MTUS2NSD3NSD3Triacsin cTriacsin cTPM4TPM4FANCIFANCIURB2URB2CDKN2ACDKN2AGRK4GRK4TNIKTNIKPAPPAPAPPACDH2CDH2NFKB1NFKB1TRIM33TRIM33GSK3BGSK3BIL1RNIL1RNPKN2PKN2PHKG1PHKG1TamatinibTamatinibCHUKCHUKADAM22ADAM22EP300EP300RIPK2RIPK2CSNK1G3CSNK1G3MAP2K4MAP2K4ADAMTSL3ADAMTSL3MSH2MSH2TRIOTRIONEXMIFNEXMIFGHRGHRMK-2206MK-2206SOX11SOX11SDCCAG8SDCCAG8MAML3MAML3TRRAPTRRAPMYCLMYCLNR2F1NR2F1RNASELRNASELPSKH2PSKH2CYP1A2CYP1A2AKT3AKT3MFSD2AMFSD2APBX1PBX1Pifithrin-muPifithrin-muALS2ALS2ISG15ISG15SHC1SHC1ELF4ELF4NCOA2NCOA2TIE1TIE1RPS6KA6RPS6KA6HEPHHEPHVCPIP1VCPIP1GRIK1GRIK1CCNB1IP1CCNB1IP1NONONONODGKGDGKGBRD4132BRD4132KALRNKALRNPPARGC1APPARGC1AManumycin AManumycin AISX-9ISX-9TNFAIP3TNFAIP3HSP90AA1HSP90AA1BMP4BMP4TET2TET2TGX-115TGX-115PPARDPPARDPKHD1PKHD1CASP1CASP1ITGA10ITGA10YAP1YAP1HOXD13HOXD13IL3IL3DDX1DDX1MLLT1MLLT1TANKTANKPDPK1PDPK1BIX01294BIX01294MIEN1MIEN1SERPINB1SERPINB1ERBB2ERBB2PLPP5PLPP5WNK1WNK1BRCA1BRCA1STARD3STARD3HSPA4HSPA4CSF3CSF3MYLK3MYLK3GRB7GRB7FedratinibFedratinibITIH6ITIH6KRASKRASNLRP1NLRP1CDX2CDX2MAP2K1MAP2K1SMAD4SMAD4PIK3CBPIK3CBNRASNRASNF1NF1SelumetinibSelumetinibDHDDSDHDDSGUCY1A2GUCY1A2LNX2LNX2BRD4BRD4PKN3PKN3Compound 23 citrateCompound 23 citrateCOPS5COPS5MALT1MALT1HDAC2HDAC2PRKXPRKXCDH11CDH11ROBO2ROBO2PRAMEPRAMETGFB1TGFB1PiperlonguminePiperlonguminePGRPGRIKZF1IKZF1NUTM1NUTM1LAMA1LAMA1MAP3K10MAP3K10XPO5XPO5NIPBLNIPBLRPS6KA5RPS6KA5PORCNPORCNDYRK2DYRK2FLNAFLNADNAAF3DNAAF3BRD63610BRD63610LRRC7LRRC7KPNA5KPNA5NOTCH1NOTCH1ORMDL3ORMDL3NYNRINNYNRINIL6STIL6STATP13A5ATP13A5TAF1LTAF1LELAVL1ELAVL1SB225002SB225002CLPTM1LCLPTM1LSETDB1SETDB1LMO2LMO2AXIN2AXIN2GRAMD1BGRAMD1BCNTN5CNTN5HIPK3HIPK3ZFP69BZFP69BLRRK2LRRK2ADAMTS2ADAMTS2PEAK1PEAK1ZFYVE9ZFYVE9HORMAD1HORMAD1FRKFRKSCHEMBL2608041SCHEMBL2608041IKZF3IKZF3STK40STK40PIP5K1BPIP5K1BCMC4CMC4RPTORRPTORCYTOCHALASIN BCYTOCHALASIN BITPR1ITPR1CDK19CDK19RFC4RFC4GLI2GLI2OSR1OSR1ULK4ULK4PLCG2PLCG2RAP1GDS1RAP1GDS1PPP3CAPPP3CAALPK2ALPK2PLCG1PLCG1ITPR2ITPR2BX-795BX-795PRKG2PRKG2SMARCA4SMARCA4TWF1TWF1MRE11MRE11FGRFGRGLG1GLG1RGL2RGL2MAP2K7MAP2K7PPP1R3APPP1R3ASTAT6STAT6RB1RB1TNNTNNGRIN2BGRIN2BKinetin ribosideKinetin ribosideATMATMFBN2FBN2PTPRDPTPRDDNAH8DNAH8IFNA2IFNA2Leucascandrolide ALeucascandrolide ANEK1NEK1LTKLTKBRDTBRDTMSH3MSH3MAP2K3MAP2K3PIK3CAPIK3CALATS2LATS2DHFRDHFRTMPOTMPOPF750PF750EPHA8EPHA8CHIR-99021CHIR-99021CTSSCTSSCSNK1DCSNK1DCYP2B6CYP2B6Compound 7d-cisCompound 7d-cisSTAT3STAT3RBM15RBM15LMTK2LMTK2MAP3K20MAP3K20TAF15TAF15ADCK2ADCK2SACSSACSTipifarnibTipifarnibMARK1MARK1

Gene-drug targets distribution

Gene Structure: PDB

Models in MARK1

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.