STK32C
Summary: The protein encoded by this gene is a member of the serine/threonine protein kinase family. It is thought that this family member is functional in brain due to its high expression levels there. DNA methylation differences have been found in this gene in monozygotic twins that are discordant for adolescent depression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| serine/threonine kinase 32C | Ensembl:ENSG00000165752 | HGNC:HGNC:21332 | PA134888050 | 10q26.3 |
GO terms in STK32C
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IEA | GO:0046872 | metal ion binding |
| BP | IBA | GO:0018105 | peptidyl-serine phosphorylation |
| BP | IBA | GO:0035556 | intracellular signal transduction |
Gene expression in normal tissue: STK32C
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in STK32C
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD887 | Compound 23 citrate | 3 |
| iGMDRD367 | Ro 28-1675 | 2 |
| iGMDRD562 | Navitoclax | 3 |
| iGMDRD420 | Leucascandrolide A | 3 |
| iGMDRD219 | Bax channel blocker | 3 |
| iGMDRD60 | Quinoclamine | 3 |
| iGMDRD267 | Oligomycin A | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in STK32C
CLASSFICATION
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