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EHBP1

Summary: This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
EH domain binding protein 1	MIM:609922	Ensembl:ENSG00000115504	HGNC:HGNC:29144	PA128394620	2p15

GO terms in EHBP1

Term Type	Evidence Type	GO Term ID	GO Des.
BP	IEA	GO:0006897	endocytosis
BP	IEA	GO:0015031	protein transport
CC	IEA	GO:0005768	endosome
CC	IDA	GO:0005829	cytosol
CC	IDA	GO:0005886	plasma membrane

Gene expression in normal tissue: EHBP1

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in EHBP1

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD126	Tipifarnib	2
iGMDRD512	nutlin 3	2
iGMDRD560	MK-2206	2
iGMDRD345	Compound 10b [PMID: 11504634]	2
iGMDRD494	Neopeltolide	5
iGMDRD446	LY 2183240	4
iGMDRD639	YK 4-279	2
iGMDRD237	ABT-751	2
iGMDRD219	Bax channel blocker	2
iGMDRD782	DC-45-A2	5
iGMDRD294	Batimastat	1
iGMDRD77	Itraconazole	6
iGMDRD329	Merck60	1
iGMDRD506	Fedratinib	3
iGMDRD366	PI-103	2
iGMDRD780	PP-30	2
iGMDRD562	Navitoclax	6
iGMDRD886	Compound 1541A	5
iGMDRD60	Quinoclamine	4
iGMDRD369	TGX-115	2
iGMDRD64	Parbendazole	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in EHBP1

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CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.