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ADARB2

Summary: This gene encodes a member of the double-stranded RNA adenosine deaminase family of RNA-editing enzymes and may play a regulatory role in RNA editing. [provided by RefSeq, Jul 2008].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
adenosine deaminase, RNA specific B2 (inactive)	MIM:602065	Ensembl:ENSG00000185736	HGNC:HGNC:227	PA24557	10p15.3

GO terms in ADARB2

Term Type	Evidence Type	GO Term ID	GO Des.
CC	IBA	GO:0005634	nucleus
CC	IEA	GO:0005634	nucleus
CC	IBA	GO:0005730	nucleolus
CC	IBA	GO:0005737	cytoplasm
BP	IBA	GO:0006382	adenosine to inosine editing
BP	IBA	GO:0006396	RNA processing
BP	IEA	GO:0006397	mRNA processing
MF	HDA	GO:0003723	RNA binding
MF	IBA	GO:0003725	double-stranded RNA binding
MF	TAS	GO:0003725	double-stranded RNA binding
MF	IBA	GO:0003726	double-stranded RNA adenosine deaminase activity
MF	TAS	GO:0003727	single-stranded RNA binding
MF	IEA	GO:0004000	adenosine deaminase activity
MF	IBA	GO:0008251	tRNA-specific adenosine deaminase activity
MF	IEA	GO:0046872	metal ion binding

Gene expression in normal tissue: ADARB2

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ADARB2

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD158	NSC141540	2
iGMDRD481	Dactolisib	2
iGMDRD267	Oligomycin A	2
iGMDRD213	SMR000068650	2
iGMDRD329	Merck60	5
iGMDRD367	Ro 28-1675	2
iGMDRD414	MST-312	3
iGMDRD82	Quiflapon	2
iGMDRD512	nutlin 3	3
iGMDRD701	NVP-AUY922	2
iGMDRD150	RITA	3
iGMDRD532	Olaparib	3
iGMDRD424	Tamatinib	1
iGMDRD345	Compound 10b [PMID: 11504634]	2
iGMDRD901	ELCPK	3
iGMDRD177	Teniposide	2
iGMDRD255	SB225002	2
iGMDRD270	Ciclosporin	2
iGMDRD801	2,4-dideoxy-DC-45-A2	2
iGMDRD52	Rotenone	2
iGMDRD782	DC-45-A2	2
iGMDRD888	Compound 44	1
iGMDRD562	Navitoclax	2
iGMDRD188	Piperlongumine	2
iGMDRD100	Zebularine	2
iGMDRD74	Idarubicin	2
iGMDRD730	Kahalalide F	3
iGMDRD887	Compound 23 citrate	2
iGMDRD64	Parbendazole	1
iGMDRD772	BRD4770	3
iGMDRD579	PF750	2
iGMDRD427	ABT737	2
iGMDRD639	YK 4-279	3
iGMDRD316	N9-Isopropyl-olomoucine	2
iGMDRD193	Fqi1	2
iGMDRD446	LY 2183240	2
iGMDRD201	SKI II	2
iGMDRD280	CYTOCHALASIN B	2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ADARB2

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.