WEE2
Summary:
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
WEE1 homolog 2 | MIM:614084 | Ensembl:ENSG00000214102 | HGNC:HGNC:19684 | PA134909633 | 7q34 |
GO terms in WEE2
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | IBA | GO:0005634 | nucleus |
CC | IDA | GO:0005654 | nucleoplasm |
CC | IDA | GO:0005829 | cytosol |
BP | IEA | GO:0000278 | mitotic cell cycle |
BP | IBA | GO:0007093 | mitotic cell cycle checkpoint |
BP | ISS | GO:0007143 | female meiotic nuclear division |
BP | IEA | GO:0018108 | peptidyl-tyrosine phosphorylation |
BP | ISS | GO:0035038 | female pronucleus assembly |
BP | IEA | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity |
BP | IBA | GO:0060631 | regulation of meiosis I |
BP | ISS | GO:0060631 | regulation of meiosis I |
BP | ISS | GO:1900194 | negative regulation of oocyte maturation |
MF | IEA | GO:0000287 | magnesium ion binding |
MF | IBA | GO:0004672 | protein kinase activity |
MF | IBA | GO:0004713 | protein tyrosine kinase activity |
MF | IEA | GO:0004715 | non-membrane spanning protein tyrosine kinase activity |
MF | IEA | GO:0005524 | ATP binding |
Gene expression in normal tissue: WEE2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene-Drug: Aster Plot
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD889 | Compound 7d-cis | 3 |
iGMDRD701 | NVP-AUY922 | 3 |
iGMDRD144 | NSC95397 | 6 |
iGMDRD61 | Kinetin riboside | 6 |
iGMDRD152 | 179324-69-7 | 1 |
iGMDRD85 | Ursolic acid | 1 |
iGMDRD634 | SCHEMBL2608041 | 3 |
iGMDRD137 | Indisulam | 2 |
iGMDRD267 | Oligomycin A | 3 |
iGMDRD329 | Merck60 | 3 |
iGMDRD100 | Zebularine | 3 |
iGMDRD871 | BRD6368 | 3 |
iGMDRD872 | BRD7137 | 3 |
iGMDRD42 | Vorinostat | 3 |
iGMDRD60 | Quinoclamine | 3 |
iGMDRD369 | TGX-115 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in WEE2