ADAM29


Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
ADAM metallopeptidase domain 29MIM:604778Ensembl:ENSG00000168594HGNC:HGNC:207PA245244q34.1

GO terms in ADAM29


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0006508proteolysis
BPTASGO:0007283spermatogenesis
CCTASGO:0005887integral component of plasma membrane
MFIEAGO:0004222metalloendopeptidase activity
MFTASGO:0008237metallopeptidase activity

Gene expression in normal tissue: ADAM29

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ADAM29


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD505Pevonedistat6
iGMDRD552AZD-17753
iGMDRD871BRD63682
iGMDRD872BRD71372
iGMDRD329Merck604
iGMDRD269Purmorphamine3
iGMDRD705Nakiterpiosin3
iGMDRD289Parthenolide3
iGMDRD481Dactolisib3
iGMDRD231Importazole3
iGMDRD77Itraconazole2
iGMDRD103SN-381
iGMDRD202Curcumin6
iGMDRD121GMX17785
iGMDRD123Isoevodiamine4
iGMDRD351GW843682X3
iGMDRD698Neratinib3
iGMDRD237ABT-7511
iGMDRD560MK-22063
iGMDRD150RITA4
iGMDRD116CD4373
iGMDRD424Tamatinib3
iGMDRD701NVP-AUY9222
iGMDRD84Lovastatin acid1
iGMDRD330BRD41322
iGMDRD584VER 1550082
iGMDRD607Ubistatin B2
iGMDRD23Gossypol3
iGMDRD356PNU-746541
iGMDRD188Piperlongumine3
iGMDRD100Zebularine3
iGMDRD887Compound 23 citrate2
iGMDRD74Idarubicin3
iGMDRD730Kahalalide F2
iGMDRD399Selumetinib1
iGMDRD577BIX012942
iGMDRD294Batimastat2
iGMDRD52Rotenone2
iGMDRD513BML-2592
iGMDRD474Avrainvillamide3
iGMDRD255SB2250025
iGMDRD466Chaetocin4
iGMDRD446LY 21832401
iGMDRD316N9-Isopropyl-olomoucine2
iGMDRD163all trans Retinoic Acid2
iGMDRD546BMS-7548073
iGMDRD494Neopeltolide2
iGMDRD483SCH-5290744
iGMDRD126Tipifarnib4
iGMDRD210AC556491
iGMDRD420Leucascandrolide A2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ADAM29

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