BTG1

Summary: This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameBTG anti-proliferation factor 1
OMIM IDMIM:109580
Ensembl IDEnsembl:ENSG00000133639
HGNC IDHGNC:HGNC:1130
PHARMGKB IDPA25450
Map Location12q21.33

GO terms in BTG1


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
BP NAS GO:0006355 regulation of transcription, DNA-templated
BP IEA GO:0006479 protein methylation
BP IEA GO:0006979 response to oxidative stress
BP IEA GO:0007283 spermatogenesis
BP IBA GO:0008285 negative regulation of cell proliferation
BP IDA GO:0008285 negative regulation of cell proliferation
Showing 1 to 6 of 25 rows rows per page

Gene expression in normal tissue: BTG1

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 11LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 2

Gene-drug pathway distribution

undefined4Chromatin histone acetylation1

Pathways in BTG1


Loading, please wait...
Database
Pathway ID
Pathway Des.
kegg hsa03018 RNA degradation - Homo sapiens (human)
wikipathways WP410 Exercise-induced Circadian Regulation
biocarta btg2pathway btg family proteins and cell cycle regulation
Showing 1 to 3 of 3 rows

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD60 Quinoclamine 2
iGMDRD427 ABT737 2
iGMDRD297 Austocystin D 2
iGMDRD42 Vorinostat 5
Showing 1 to 4 of 5 rows

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in BTG1

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.