NAV3
Summary: This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:611629 Ensembl IDEnsembl:ENSG00000067798 HGNC IDHGNC:HGNC:15998 PHARMGKB IDPA31453 Map Location12q21.2 | |||||
GO terms in NAV3
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0005524 | ATP binding |
| MF | IDA | GO:0008017 | microtubule binding |
| CC | IEA | GO:0005640 | nuclear outer membrane |
| CC | IMP | GO:1990752 | microtubule end |
| BP | IMP | GO:0007026 | negative regulation of microtubule depolymerization |
| BP | IBA | GO:0007399 | nervous system development |
Gene expression in normal tissue: NAV3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NAV3
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NAV3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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