GO terms in PI4KB


Term TypeEvidence TypeGO Term IDGO Des.
BPTASGO:0006661phosphatidylinositol biosynthetic process
BPTASGO:0006898receptor-mediated endocytosis
BPTASGO:0007165signal transduction
BPIBAGO:0046854phosphatidylinositol phosphorylation
BPIEAGO:0046854phosphatidylinositol phosphorylation
BPIBAGO:0048015phosphatidylinositol-mediated signaling
CCIDAGO:0000139Golgi membrane
CCTASGO:0000139Golgi membrane
CCIBAGO:0005737cytoplasm
CCTASGO:0005737cytoplasm
CCIEAGO:0005741mitochondrial outer membrane
CCTASGO:0005768endosome
CCTASGO:0005829cytosol
CCIBAGO:0016020membrane
CCIEAGO:0030867rough endoplasmic reticulum membrane
CCIEAGO:0048471perinuclear region of cytoplasm
MFIBAGO:00044301-phosphatidylinositol 4-kinase activity
MFIDAGO:00044301-phosphatidylinositol 4-kinase activity
MFTASGO:00044301-phosphatidylinositol 4-kinase activity
MFIPIGO:0005515protein binding
MFIEAGO:0005524ATP binding
MFIBAGO:0052742phosphatidylinositol kinase activity
MFIDAGO:007188914-3-3 protein binding

Gene expression in normal tissue: PI4KB

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PI4KB


DatabasePathway IDPathway Des.
reactomeR-HSA-1430728Metabolism
reactomeR-HSA-1483255PI Metabolism
reactomeR-HSA-1483257Phospholipid metabolism
reactomeR-HSA-1660514Synthesis of PIPs at the Golgi membrane
reactomeR-HSA-556833Metabolism of lipids
humancycPWY-6351D-myo-inositol (1,4,5)-trisphosphate biosynthesis
humancycPWY-63523-phosphoinositide biosynthesis
humancycPWY-6371superpathway of inositol phosphate compounds
pidavb3_integrin_pathwayIntegrins in angiogenesis
kegghsa00562Inositol phosphate metabolism - Homo sapiens (human)
kegghsa04070Phosphatidylinositol signaling system - Homo sapiens (human)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD871BRD63685
iGMDRD286Nsc 6328393
iGMDRD329Merck605
iGMDRD552AZD-17751
iGMDRD42Vorinostat1
iGMDRD158NSC1415403
iGMDRD137Indisulam8
iGMDRD251ML1621
iGMDRD5Tyrphostin AG 14783
iGMDRD289Parthenolide3
iGMDRD267Oligomycin A1
iGMDRD85Ursolic acid1
iGMDRD351GW843682X3
iGMDRD177Teniposide6
iGMDRD154NSC237663
iGMDRD945ML2143
iGMDRD307Manumycin A3
iGMDRD512nutlin 33
iGMDRD188Piperlongumine3
iGMDRD887Compound 23 citrate3
iGMDRD399Selumetinib3
iGMDRD577BIX012942
iGMDRD888Compound 443
iGMDRD562Navitoclax3
iGMDRD780PP-304
iGMDRD60Quinoclamine3
iGMDRD23Gossypol6
iGMDRD138PX 123
iGMDRD171Pemetrexed3
iGMDRD885Compound 1103
iGMDRD446LY 21832403
iGMDRD61Kinetin riboside2
iGMDRD126Tipifarnib3
iGMDRD151CHM-13
iGMDRD554CHEMBL14341373
iGMDRD772BRD47703
iGMDRD420Leucascandrolide A3
iGMDRD546BMS-7548073
iGMDRD144NSC953973
iGMDRD483SCH-5290746
iGMDRD494Neopeltolide1
iGMDRD484Pluripotin3
iGMDRD781Sirolimus3

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PI4KB

​​​​