PI4KB

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namephosphatidylinositol 4-kinase beta
OMIM IDMIM:602758
Ensembl IDEnsembl:ENSG00000143393
HGNC IDHGNC:HGNC:8984
PHARMGKB IDPA162399420
Map Location1q21.3

GO terms in PI4KB


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Term Type
Evidence Type
GO Term ID
GO Des.
BP TAS GO:0006661 phosphatidylinositol biosynthetic process
BP TAS GO:0006898 receptor-mediated endocytosis
BP TAS GO:0007165 signal transduction
BP IBA GO:0046854 phosphatidylinositol phosphorylation
BP IEA GO:0046854 phosphatidylinositol phosphorylation
BP IBA GO:0048015 phosphatidylinositol-mediated signaling
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Gene expression in normal tissue: PI4KB

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 77OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 36LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 3BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: undefined model num: 3UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: Endometrial Carcinoma (UCEC) model num: 6BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 9

Gene-drug pathway distribution

undefined33Chromatin histone acetylation2One carbon pool by folate1Longevity regulating pathway1Biosynthesis of secondary metabolites1IGFR signaling1ERK MAPK signaling1DNA replication1Cell cycle1Apoptosis regulation1

Pathways in PI4KB


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1430728 Metabolism
reactome R-HSA-1483255 PI Metabolism
reactome R-HSA-1483257 Phospholipid metabolism
reactome R-HSA-1660514 Synthesis of PIPs at the Golgi membrane
reactome R-HSA-556833 Metabolism of lipids
humancyc PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD871 BRD6368 5
iGMDRD286 Nsc 632839 3
iGMDRD329 Merck60 5
iGMDRD552 AZD-1775 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PI4KB

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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