PEAK1
Summary: This gene encodes a non-receptor tyrosine kinase that is a member of the new kinase family three (NFK3) family. In migrating cells, the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation. This protein may play a role in the regulation of cell migration, proliferation and cancer metastasis. [provided by RefSeq, Mar 2014].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:614248 Ensembl IDEnsembl:ENSG00000173517 HGNC IDHGNC:HGNC:29431 PHARMGKB IDPA166123722 Map Location15q24.3 | |||||
GO terms in PEAK1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0006468 | protein phosphorylation |
| BP | IDA | GO:0016477 | cell migration |
| BP | IMP | GO:0016477 | cell migration |
| BP | IEA | GO:0018108 | peptidyl-tyrosine phosphorylation |
| BP | IDA | GO:0034446 | substrate adhesion-dependent cell spreading |
| BP | IDA | GO:0046777 | protein autophosphorylation |
Gene expression in normal tissue: PEAK1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PEAK1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PEAK1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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