ZNF521
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| zinc finger protein 521 | MIM:610974 | Ensembl:ENSG00000198795 | HGNC:HGNC:24605 | PA134956321 | 18q11.2 |
GO terms in ZNF521
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | IEA | GO:0003677 | DNA binding |
| MF | IPI | GO:0019904 | protein domain specific binding |
| MF | IEA | GO:0046872 | metal ion binding |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IEA | GO:0006357 | regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0048663 | neuron fate commitment |
| CC | IDA | GO:0005634 | nucleus |
Gene expression in normal tissue: ZNF521
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ZNF521
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-212436 | Generic Transcription Pathway |
| reactome | R-HSA-73857 | RNA Polymerase II Transcription |
| reactome | R-HSA-74160 | Gene expression (Transcription) |
| reactome | R-HSA-8878166 | Transcriptional regulation by RUNX2 |
| reactome | R-HSA-8940973 | RUNX2 regulates osteoblast differentiation |
| reactome | R-HSA-8941326 | RUNX2 regulates bone development |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD151 | CHM-1 | 3 |
| iGMDRD126 | Tipifarnib | 3 |
| iGMDRD484 | Pluripotin | 5 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 3 |
| iGMDRD144 | NSC95397 | 2 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD446 | LY 2183240 | 3 |
| iGMDRD341 | Triacsin c | 4 |
| iGMDRD883 | CIL55A | 3 |
| iGMDRD679 | Bistramide A | 3 |
| iGMDRD158 | NSC141540 | 3 |
| iGMDRD137 | Indisulam | 2 |
| iGMDRD121 | GMX1778 | 3 |
| iGMDRD870 | BRD63610 | 3 |
| iGMDRD801 | 2,4-dideoxy-DC-45-A2 | 4 |
| iGMDRD782 | DC-45-A2 | 2 |
| iGMDRD434 | BMS-536924 | 3 |
| iGMDRD705 | Nakiterpiosin | 9 |
| iGMDRD872 | BRD7137 | 2 |
| iGMDRD882 | CIL41 | 3 |
| iGMDRD286 | Nsc 632839 | 4 |
| iGMDRD414 | MST-312 | 2 |
| iGMDRD322 | FK 866 | 3 |
| iGMDRD886 | Compound 1541A | 2 |
| iGMDRD505 | Pevonedistat | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ZNF521
CLASSFICATION
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