FOXO1


Summary: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:136533
PHARMGKB IDPA28237
Map Location13q14.11

GO terms in FOXO1


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0000122 negative regulation of transcription by RNA polymerase II
BP IEA GO:0000122 negative regulation of transcription by RNA polymerase II
BP IEA GO:0001568 blood vessel development
BP ISS GO:0001659 temperature homeostasis
BP ISS GO:0001678 cellular glucose homeostasis
BP IEA GO:0006351 transcription, DNA-templated
Showing 1 to 6 of 68 rows rows per page

Gene expression in normal tissue: FOXO1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined25Longevity regulating pathway1Genome integrity1Ferroptosis1One carbon pool by folate1p53 pathway1Leukocyte transendothelial migration1

Pathways in FOXO1


Loading, please wait...
Database
Pathway ID
Pathway Des.
biocarta aktpathway akt signaling pathway
reactome R-HSA-1257604 PIP3 activates AKT signaling
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1266738 Developmental Biology
reactome R-HSA-1280215 Cytokine Signaling in Immune system
reactome R-HSA-162582 Signal Transduction
Showing 1 to 6 of 86 rows rows per page

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD329 Merck60 1
iGMDRD577 BIX01294 2
iGMDRD780 PP-30 1
iGMDRD286 Nsc 632839 7
Showing 1 to 4 of 31 rows rows per page

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in FOXO1

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​