VPS13B


Summary: This gene encodes a potential transmembrane protein that may function in vesicle-mediated transport and sorting of proteins within the cell. This protein may play a role in the development and the function of the eye, hematological system, and central nervous system. Mutations in this gene have been associated with Cohen syndrome. Multiple splice variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
vacuolar protein sorting 13 homolog BMIM:607817Ensembl:ENSG00000132549HGNC:HGNC:2183PA266998q22.2

GO terms in VPS13B


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0015031protein transport

Gene expression in normal tissue: VPS13B

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in VPS13B


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD446LY 21832402
iGMDRD152179324-69-74
iGMDRD280CYTOCHALASIN B1
iGMDRD394BX-7952
iGMDRD466Chaetocin2
iGMDRD297Austocystin D1
iGMDRD151CHM-13
iGMDRD126Tipifarnib5
iGMDRD772BRD47702
iGMDRD144NSC953979
iGMDRD484Pluripotin3
iGMDRD494Neopeltolide5
iGMDRD887Compound 23 citrate2
iGMDRD188Piperlongumine5
iGMDRD100Zebularine2
iGMDRD398Sepantronium2
iGMDRD577BIX012945
iGMDRD474Avrainvillamide4
iGMDRD270Ciclosporin3
iGMDRD255SB2250021
iGMDRD318PAC-14
iGMDRD341Triacsin c2
iGMDRD351GW843682X5
iGMDRD698Neratinib3
iGMDRD901ELCPK1
iGMDRD871BRD63682
iGMDRD329Merck604
iGMDRD246NPC262
iGMDRD300Tozasertib3
iGMDRD505Pevonedistat1
iGMDRD322FK 8662
iGMDRD137Indisulam2
iGMDRD121GMX17782
iGMDRD158NSC1415402
iGMDRD434BMS-5369243
iGMDRD289Parthenolide2
iGMDRD705Nakiterpiosin4

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in VPS13B

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