HDLBP


Summary: The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation. [provided by RefSeq, Mar 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
high density lipoprotein binding proteinMIM:142695Ensembl:ENSG00000115677HGNC:HGNC:4857PA292352q37.3

GO terms in HDLBP


Term TypeEvidence TypeGO Term IDGO Des.
MFHDAGO:0003723RNA binding
MFIPIGO:0005515protein binding
MFTASGO:0008289lipid binding
MFHDAGO:0045296cadherin binding
CCIEAGO:0005634nucleus
CCIDAGO:0005829cytosol
CCTASGO:0005886plasma membrane
CCIEAGO:0034364high-density lipoprotein particle
BPIEAGO:0006869lipid transport
BPIEAGO:0008203cholesterol metabolic process
BPTASGO:0034384high-density lipoprotein particle clearance

Gene expression in normal tissue: HDLBP

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in HDLBP


DatabasePathway IDPathway Des.
reactomeR-HSA-174824Plasma lipoprotein assembly, remodeling, and clearance
reactomeR-HSA-382551Transport of small molecules
reactomeR-HSA-8964011HDL clearance
reactomeR-HSA-8964043Plasma lipoprotein clearance

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD405PIK-751
iGMDRD116CD4375
iGMDRD532Olaparib3
iGMDRD512nutlin 33
iGMDRD307Manumycin A3
iGMDRD132(-)-gallocatechin-3-O-gallate3
iGMDRD901ELCPK2
iGMDRD177Teniposide3
iGMDRD499PDMP3
iGMDRD85Ursolic acid1
iGMDRD705Nakiterpiosin3
iGMDRD105Triptolide2
iGMDRD221Tamoxifen3
iGMDRD103SN-383
iGMDRD121GMX17782
iGMDRD202Curcumin3
iGMDRD137Indisulam3
iGMDRD158NSC1415402
iGMDRD82Quiflapon3
iGMDRD505Pevonedistat3
iGMDRD552AZD-17753
iGMDRD246NPC262
iGMDRD329Merck602
iGMDRD414MST-3123
iGMDRD484Pluripotin6
iGMDRD144NSC953972
iGMDRD1008SR-II-138A1
iGMDRD772BRD47703
iGMDRD420Leucascandrolide A2
iGMDRD151CHM-11
iGMDRD193Fqi11
iGMDRD318PAC-13
iGMDRD885Compound 1104
iGMDRD441TW 375
iGMDRD8012,4-dideoxy-DC-45-A23
iGMDRD870BRD636103
iGMDRD8024-methylfasudil2
iGMDRD138PX 121
iGMDRD356PNU-746542
iGMDRD23Gossypol6
iGMDRD524ISX-93
iGMDRD64Parbendazole2
iGMDRD188Piperlongumine2
iGMDRD399Selumetinib2
iGMDRD74Idarubicin3

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in HDLBP

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