HDLBP


Summary: The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation. [provided by RefSeq, Mar 2016].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
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GO terms in HDLBP


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Term Type
Evidence Type
GO Term ID
GO Des.
MF HDA GO:0003723 RNA binding
MF IPI GO:0005515 protein binding
MF TAS GO:0008289 lipid binding
MF HDA GO:0045296 cadherin binding
CC IEA GO:0005634 nucleus
CC IDA GO:0005829 cytosol
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Gene expression in normal tissue: HDLBP

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined36Apoptosis regulation2DNA replication2ERK MAPK signaling1Biosynthesis of secondary metabolites1Genome integrity1Stilbenoid, diarylheptanoid and gingerol biosynthesis1Drug metabolism - cytochrome P4501

Pathways in HDLBP


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Database
Pathway ID
Pathway Des.
reactome R-HSA-174824 Plasma lipoprotein assembly, remodeling, and clearance
reactome R-HSA-382551 Transport of small molecules
reactome R-HSA-8964011 HDL clearance
reactome R-HSA-8964043 Plasma lipoprotein clearance
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD405 PIK-75 1
iGMDRD116 CD437 5
iGMDRD532 Olaparib 3
iGMDRD512 nutlin 3 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in HDLBP

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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